HYCC2 and TTC7B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HYCC2	TTC7B
Description		hyccin PI4KA lipid kinase complex subunit 2	tetratricopeptide repeat domain 7B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane	Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Phosphatidylinositol Phosphate Biosynthetic Process Protein Localization To Plasma Membrane	Phosphatidylinositol Phosphate Biosynthetic Process Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS			3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Anxiety disorder ( 25390645) Cytomegalovirus antibody response ( 21993531) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Nevus count or cutaneous melanoma ( 30429480) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Schizophrenia ( 33169155) Severe autoimmune type 2 diabetes ( 34737425) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: APP C2orf69 DAPK1 GOLGA2 MEOX1 PDCL2 TRIM27 TTC7B	5 interacting genes: COG6 DSCAM HYCC2 RAB3IL1 RUSC1
Entrez ID		285172	145567
HPRD ID		11345	18503
Ensembl ID		ENSG00000155744	ENSG00000165914
Uniprot IDs		A0A804HIT6 B3KUG1 Q8IXS8	Q6PIF1 Q86TV6
PDB IDs			5DSE 6BQ1 9B9G 9BAX
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Reproductive Process Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of NMDA Receptor Activity DAPK1-calmodulin Complex Regulation Of Autophagy Positive Regulation Of Autophagic Cell Death Positive Regulation Of Protein Glycosylation Negative Regulation Of Autophagy Sclerotome Development Somite Specification Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Positive Regulation Of Supramolecular Fiber Organization Regulation Of Toll Signaling Pathway Positive Regulation Of Autophagy Golgi Disassembly
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