SLC13A5 and KRTAP12-3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC13A5	KRTAP12-3
Description		solute carrier family 13 member 5	keratin associated protein 12-3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Membrane	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Organic Acid:sodium Symporter Activity Protein Binding Citrate Transmembrane Transporter Activity Succinate Transmembrane Transporter Activity Tricarboxylic Acid Transmembrane Transporter Activity Symporter Activity Solute:sodium Symporter Activity Sodium:dicarboxylate Symporter Activity Transmembrane Transporter Activity Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Monoatomic Ion Transport Sodium Ion Transport Tricarboxylic Acid Transport Oxaloacetate Transport Fumarate Transport Alpha-ketoglutarate Transport Succinate Transport Citrate Transport Tricarboxylic Acid Transmembrane Transport Sodium Ion Transmembrane Transport Transmembrane Transport Cellular Response To Lithium Ion Succinate Transmembrane Transport Organic Acid Transmembrane Transport
Pathways		SLC-mediated transport of organic anions	Keratinization
Drugs
Diseases
GWAS		Economic and political preferences (time) ( 22566634) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		18 interacting genes: ADAMTSL4 CD79A CYSRT1 GJA8 GOLM1 KLHL20 KRTAP1-3 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP5-2 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 MDFI	145 interacting genes: ADAMTSL3 ADAMTSL4 AGXT ALDH3B1 BCL6B BMP7 C11orf87 C22orf39 CARD10 CATSPER1 CBX2 CELF5 CHIC2 CHRD CHRNG CNNM3 COL8A1 CRCT1 CREB5 CYSRT1 DALRD3 DHRS1 DHX57 DNAL4 DOCK2 FASLG FBXW5 GLRX3 GNE GTF3C5 HOXA1 ITGB4 JOSD1 KPRP KRT20 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP19-7 KRTAP3-3 KRTAP4-2 KRTAP4-4 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LIF LMNTD2 LNX1 LYVE1 MAPKBP1 MEOX2 MISP MOBP NBPF19 NKD1 NMU NOTCH2NLA NPDC1 NR1D2 NR4A3 NUFIP2 OTX1 OXER1 P2RX4 P2RY6 P3H3 P4HB PDE9A PDGFRB PGAP6 PHLDA1 POU4F2 PTGDS PTPMT1 R3HDM2 RSPO2 SELENOM SHFL SLC13A5 SLC15A2 SLC23A1 SMCP SPATA3 SPRY1 TCEA2 TCEANC TFAP2D TMIE TNP2 TNS2 TTPA UTP23 UXT VASN VGLL3 VSTM4 WDR25 WNT11 YY1 ZDHHC1 ZNF101 ZNF124 ZNF138 ZNF20 ZNF408 ZNF417 ZNF439 ZNF440 ZNF467 ZNF490 ZNF491 ZNF497 ZNF578 ZNF587 ZNF648 ZNF696 ZNF80 ZNF835 ZNF837 ZSCAN21
Entrez ID		284111	386683
HPRD ID		10512	11199
Ensembl ID		ENSG00000141485	ENSG00000205439
Uniprot IDs		Q86YT5	P60328
PDB IDs		7JSJ 7JSK 8UVB 8UVH
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Identical Protein Binding Type II Interferon Binding Pigment Cell Development	Keratinization Intermediate Filament Epidermis Development Keratin Filament Protein Binding Tissue Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Regulation Of Transcription By RNA Polymerase II Identical Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
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