NEAT1 and GAR1

Number of citations of the paper that reports this interaction (PubMedID 32140098)
39

Data Source:
BioGRID (unspecified method)

		NEAT1	GAR1
Description		nuclear paraspeckle assembly transcript 1	GAR1 ribonucleoprotein
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex Paraspeckles	Chromosome, Telomeric Region Fibrillar Center Nucleus Nucleoplasm Telomerase Holoenzyme Complex Nucleolus Cajal Body Box H/ACA SnoRNP Complex Box H/ACA ScaRNP Complex Box H/ACA Telomerase RNP Complex Ribonucleoprotein Complex
	Molecular Function	MiRNA Binding Chromatin-protein Adaptor Activity Molecular Condensate Scaffold Activity MiRNA Inhibitor Activity Via Base-pairing RISC Complex Binding	RNA Binding Protein Binding Box H/ACA SnoRNA Binding Telomerase RNA Binding
	Biological Process	LncRNA-mediated Post-transcriptional Gene Silencing Chromatin Organization Regulation Of MRNA Export From Nucleus Nuclear Body Organization MiRNA-mediated Post-transcriptional Gene Silencing Positive Regulation Of Inflammatory Response Positive Regulation Of Synoviocyte Proliferation Positive Regulation Of MiRNA Catabolic Process	SnoRNA Guided RRNA Pseudouridine Synthesis Pseudouridine Synthesis RRNA Processing Telomere Maintenance Via Telomerase Ribosome Biogenesis
Pathways			Telomere Extension By Telomerase rRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Glaucoma (primary open-angle) ( 29891935) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172)
Interacting Genes		12 interacting genes: CTSD EGR1 GAR1 HACD3 MPC2 NEDD4L PINK1 RIMBP2 TRAF6 TUBB4A TUBB4B USP9X	8 interacting genes: DSCR9 FOXP1 LARP7 NEAT1 PCBP2 SMN1 SMN2 UBC
Entrez ID		283131	54433
HPRD ID			07569
Ensembl ID		ENSG00000245532	ENSG00000109534
Uniprot IDs			Q9NY12
PDB IDs			7BGB 7TRC 7V9A 8OUE 8OUF
Enriched GO Terms of Interacting Partners?		Receptor Metabolic Process Protein Kinase B Binding Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Receptor Recycling Regulation Of Protein Localization Interleukin-1-mediated Signaling Pathway Positive Regulation Of Post-translational Protein Modification Mitochondrial Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Organelle Organization Antigen Processing And Presentation Of Exogenous Antigen Positive Regulation Of Glomerular Metanephric Mesangial Cell Proliferation Regulation Of Biological Quality Regulation Of Post-translational Protein Modification Cellular Response To Interleukin-8 Protein Ubiquitination K11-linked Deubiquitinase Activity Canonical NF-kappaB Signal Transduction Antigen Processing And Presentation Of Peptide Antigen Insulin Catabolic Process Aspartic-type Peptidase Activity Autophagosome Organization Cysteine-type Endopeptidase Activity Antigen Processing And Presentation Autophagosome Assembly Insulin Receptor Recycling Positive Regulation Of Protein Metabolic Process Hemi-methylated DNA-binding Enzyme Binding Positive Regulation Of Protein Modification Process Cellular Response To Mycophenolic Acid Circadian Temperature Homeostasis Glomerular Mesangial Cell Proliferation Cellular Response To Heparin Regulation Of Progesterone Biosynthetic Process Response To Ischemia BMP Signaling Pathway Regulation Of Protein Metabolic Process Protein K48-linked Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Positive Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Regulation Of Protein Stability Structural Constituent Of Cytoskeleton Internode Region Of Axon Intercellular Bridge Negative Regulation Of Sodium Ion Import Across Plasma Membrane	SMN Complex Gemini Of Cajal Bodies SMN-Sm Protein Complex DNA-templated Transcription Termination MRNA Metabolic Process Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly RNA Binding Cajal Body RNA Splicing U6 2'-O-snRNA Methylation Cytoplasmic Ribonucleoprotein Granule MRNA Processing Positive Regulation Of Interleukin-21 Production Box C/D Sno(s)RNA 3'-end Processing MiRNA Inhibitor Activity Via Base-pairing RNA Metabolic Process Perikaryon Z Disc Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of SnRNA Transcription By RNA Polymerase II 7SK SnRNP RISC Complex Binding Positive Regulation Of Synoviocyte Proliferation LncRNA-mediated Post-transcriptional Gene Silencing Nucleoplasm Promoter-enhancer Loop Anchoring Activity Regulation Of Macrophage Colony-stimulating Factor Production SnRNA Modification Positive Regulation Of MiRNA Catabolic Process Viral RNA Genome Replication Osteoclast Development Regulation Of Endothelial Tube Morphogenesis Protein-RNA Complex Assembly Positive Regulation Of B Cell Receptor Signaling Pathway RNA Splicing, Via Transesterification Reactions Monocyte Activation Endothelial Cell Activation 7SK SnRNA Binding Positive Regulation Of Protein Localization To Cajal Body Paraspeckles Regulation Of MRNA Export From Nucleus IRES-dependent Viral Translational Initiation T Follicular Helper Cell Differentiation Regulation Of Defense Response RNA Processing Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development U6 SnRNA Binding Negative Regulation Of B Cell Apoptotic Process
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