TMEM97 and CLSTN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM97	CLSTN3
Description		transmembrane protein 97	calsyntenin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Lysosome Endoplasmic Reticulum Rough Endoplasmic Reticulum Plasma Membrane Membrane Rough Endoplasmic Reticulum Membrane Nuclear Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Plasma Membrane Cell Surface Postsynaptic Density Membrane Dendrite Protein-containing Complex Cell Projection Organelle Membrane Contact Site Synapse Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Protein Binding Oxysterol Binding Cholesterol Binding	Enzyme Inhibitor Activity Calcium Ion Binding Protein Binding Neurexin Family Protein Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Regulation Of Cell Growth Regulation Of Intracellular Lipid Transport Regulation Of Intracellular Cholesterol Transport Cholesterol Homeostasis Positive Regulation Of Wound Healing Positive Regulation Of Lipoprotein Transport	Regulation Of Cell Growth Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Protein Secretion Negative Regulation Of Lipid Storage L-ascorbic Acid Metabolic Process Synaptic Transmission, Glutamatergic Positive Regulation Of Synaptic Transmission Positive Regulation Of Lipid Catabolic Process Synaptic Transmission, GABAergic Regulation Of Synapse Assembly Positive Regulation Of Synapse Assembly Sympathetic Neuron Projection Extension Cell-cell Adhesion Cold-induced Thermogenesis Lipid Droplet Fusion Negative Regulation Of Lipid Droplet Fusion Positive Regulation Of Protein Localization To Synapse Excitatory Synapse Assembly Inhibitory Synapse Assembly Regulation Of Excitatory Synapse Assembly Negative Regulation Of Excitatory Synapse Assembly Regulation Of Presynapse Assembly Positive Regulation Of Inhibitory Synapse Assembly Adaptive Thermogenesis
Pathways
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Osteoprotegerin levels ( 25080503)	Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Schizophrenia ( 30285260)
Interacting Genes		75 interacting genes: ADCYAP1R1 APP AQP12B AQP2 AQP6 ARL13B ASZ1 ATP6AP2 BCL2L13 BIK CD53 CD74 CD79A CGRRF1 CLDN7 CLSTN3 CPLX4 CRLF3 EBP ERAL1 ERGIC3 FAM209A FFAR2 FKBP7 FRMD3 FXYD3 GJA8 GJB3 GJB5 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LEUTX LHFPL5 LIME1 LRRC59 MFF MRM1 MTIF3 MUC1 NDUFAF1 NDUFAF2 NEMP1 ORC1 PDCD1LG2 PDZK1IP1 PLP1 POLDIP2 PSCA REEP1 RHCG RNF167 RNF170 SAR1A SGPL1 SLC10A1 SLC14A1 SLC14A2 SLC18A1 SLC35H1 SPINT1 SSMEM1 TADA1 TBC1D29P TMEM106C TMEM14B TMEM45B TMEM52B TMEM79 TMX2 UTP4 VSIR	12 interacting genes: APBA2 CMTM7 MAL NKG7 OLFM4 PGAP2 RSPH1 TMEM107 TMEM54 TMEM97 TRAM1L1 ZDHHC22
Entrez ID		27346	9746
HPRD ID		14343	16725
Ensembl ID		ENSG00000109084	ENSG00000139182
Uniprot IDs		Q5BJF2	Q9BQT9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Water Transport One-carbon Compound Transport Fluid Transport Protein Binding Water Channel Activity Endoplasmic Reticulum Membrane Connexin Complex Endoplasmic Reticulum Gap Junction Channel Activity Plasma Membrane B Cell Receptor Complex Water Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Mitochondrial Membrane Gap Junction Urea Transmembrane Transporter Activity Transmembrane Transport
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