PDLIM3 and REEP5

		PDLIM3	REEP5
Description		PDZ and LIM domain 3	receptor accessory protein 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Adherens Junction Actin Cytoskeleton Z Disc Filamentous Actin	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Actin Binding Protein Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Metal Ion Binding Muscle Alpha-actinin Binding	Protein Binding
	Biological Process	Actin Filament Organization Heart Development Actin Cytoskeleton Organization Muscle Structure Development	Endoplasmic Reticulum Organization Regulation Of Intracellular Transport Endoplasmic Reticulum Membrane Organization
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057) Daytime nap ( 33568662) Reaction time ( 29844566)
Interacting Genes		12 interacting genes: ABCA1 ACTN2 FHL1 MYOT MYOZ2 MYOZ3 MYPN PALLD RANBP2 REEP5 RHOU RYR1	22 interacting genes: ABHD4 ARFGAP1 ARFIP2 CD14 CHRM5 CPOX EDC3 GPX3 GTF2H1 HBEGF LGR5 NUDT3 PBX3 PDK4 PDLIM3 PITPNC1 RAB5B RABAC1 RGS2 SNX1 TENT4A VKORC1
Entrez ID		27295	7905
HPRD ID		08388	15918
Ensembl ID		ENSG00000154553	ENSG00000129625
Uniprot IDs		A0A087WYF8 A0A2U3TZH4 Q53GG5	Q00765
PDB IDs
Enriched GO Terms of Interacting Partners?		Z Disc FATZ Binding Actin Binding Actin Cytoskeleton Actin Cytoskeleton Organization Sarcomere Organization Actin Filament-based Process Sarcomere Channel Activator Activity Telethonin Binding Muscle Alpha-actinin Binding Actomyosin Structure Organization Dendrite Self-avoidance Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules I Band Focal Adhesion Positive Regulation Of Potassium Ion Transport Cell-cell Adhesion Mediator Activity Sarcoplasmic Reticulum Membrane Structural Constituent Of Muscle Cytoskeleton Organization Axon Guidance Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Neuron Projection Guidance Podosome Neuron Recognition Organelle Organization Sphingolipid Floppase Activity Actin Filament Uncapping Regulation Of Intracellular Transport Cytoskeletal Protein Binding Sarcoplasmic Reticulum Striated Muscle Cell Development Response To Vitamin B3 Positive Regulation Of High-density Lipoprotein Particle Assembly Apolipoprotein A-I Receptor Activity Titin Z Domain Binding Cytoplasmic Periphery Of The Nuclear Pore Complex Ryanodine Receptor Complex Regulation Of Potassium Ion Transport Actin Filament Regulation Of High-density Lipoprotein Particle Assembly Muscle Cell Development Phospholipase C-activating Angiotensin-activated Signaling Pathway Ryanodine-sensitive Calcium-release Channel Activity Skeletal Muscle Fiber Adaptation Cell Adhesion Plasma Membrane Bounded Cell Projection Organization Axon Phosphatidylserine Floppase Activity
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