SULT1C4 and GPR45

		SULT1C4	GPR45
Description		sulfotransferase family 1C member 4	G protein-coupled receptor 45
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Plasma Membrane Membrane
	Molecular Function	Aryl Sulfotransferase Activity Sulfotransferase Activity Transferase Activity	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Ethanol Catabolic Process Xenobiotic Metabolic Process Flavonoid Metabolic Process Doxorubicin Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		Cytosolic sulfonation of small molecules Paracetamol ADME	G alpha (s) signalling events
Drugs		Ritodrine
Diseases
GWAS		Eyebrow thickness ( 26926045) Urinary albumin-to-creatinine ratio ( 32600054)	Body mass index ( 26426971) Menarche (age at onset) ( 25231870 27182965)
Interacting Genes		1 interacting genes: GPR45	4 interacting genes: OTX2 PLEKHB2 REV1 SULT1C4
Entrez ID		27233	11250
HPRD ID		07461	05325
Ensembl ID		ENSG00000198075	ENSG00000135973
Uniprot IDs		O75897 Q6PD90	B5B0C1 Q9Y5Y3
PDB IDs		2AD1 2GWH
Enriched GO Terms of Interacting Partners?			Primitive Streak Formation Positive Regulation Of Embryonic Development Eukaryotic Initiation Factor 4E Binding Positive Regulation Of Gastrulation Regulation Of Gastrulation Doxorubicin Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Ethanol Metabolic Process Flavonoid Metabolic Process Sulfation Aryl Sulfotransferase Activity Ethanol Catabolic Process Error-free Translesion Synthesis Deoxycytidyl Transferase Activity Error-prone Translesion Synthesis DNA-directed DNA Polymerase Activity Translesion Synthesis Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Midbrain Development Dopaminergic Neuron Differentiation Alcohol Catabolic Process Postreplication Repair Sulfotransferase Activity Phosphatidylinositol-3,4,5-trisphosphate Binding DNA Synthesis Involved In DNA Repair Secondary Metabolic Process
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