RSPH14 and RSPH3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RSPH14	RSPH3
Description		radial spoke head 14 homolog	radial spoke head 3
Image
GO Annotations	Cellular Component	Radial Spoke Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection	Radial Spoke Head Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection 9+2 Motile Cilium
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Serum parathyroid hormone levels ( 27927781)	Attention deficit hyperactivity disorder ( 32279069) Bladder cancer (smoking interaction) ( 24662972) Celiac disease ( 25920553) Lipoprotein (a) levels ( 26377243) Prepulse inhibition of the startle response ( 31596458) Systemic lupus erythematosus ( 28714469)
Interacting Genes		40 interacting genes: ABI2 AGAP1 ALS2CL AP1M1 AP2M1 BPIFA1 CCDC102B CDR2 CNTROB COG6 EPS8 FHL3 GABPB1 GOLGA2 JUP KASH5 KIFC3 KRT15 KRT31 KRT40 KRT75 KRT76 LZTS1 MNS1 PIBF1 POLR1C REL RPH3AL RSPH3 SEPTIN12 SMAD4 TCF4 TRAF2 TRIM27 TRIM50 TRIM69 TRIM7 VPS9D1 ZNF474 ZNF629	9 interacting genes: APP DPY30 FAM124B HSPB1 MLH1 PRKAR1A ROPN1L RSPH14 TAGAP
Entrez ID		27156	83861
HPRD ID		16136	15279
Ensembl ID		ENSG00000100218	ENSG00000130363
Uniprot IDs		Q9UHP6	Q86UC2
PDB IDs		8J07	8J07
Enriched GO Terms of Interacting Partners?		Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Organelle Organization Structural Molecule Activity Protein Binding Identical Protein Binding Zonula Adherens Sebaceous Gland Development Clathrin Adaptor Complex Centrosome Separation Positive Regulation Of Actin Nucleation Small GTPase Binding Innate Immune Response Epithelial Cell-cell Adhesion Clathrin Adaptor Activity	Radial Spoke Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Microtubule-based Transport Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Positive Regulation Of Interleukin-1 Beta Production Microtubule-based Process Negative Regulation Of Protein Kinase C Signaling Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Interleukin-1 Production Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Axo-dendritic Transport Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Microtubule-based Movement Regulation Of Interleukin-1 Beta Production Protein Kinase C Inhibitor Activity Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Male Meiosis Chromosome Segregation MutLalpha Complex Chiasma Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Gene Expression Positive Regulation Of Chemotaxis Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response
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