TRAPPC3 and TRAPPC2L

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, biochemical)
HPRD (two hybrid)

		TRAPPC3	TRAPPC2L
Description		trafficking protein particle complex subunit 3	trafficking protein particle complex subunit 2L
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol TRAPP Complex Cis-Golgi Network Membrane TRAPPII Protein Complex TRAPPIII Protein Complex	Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm TRAPPII Protein Complex TRAPPIII Protein Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Vesicle Coating Vesicle-mediated Transport Golgi Vesicle Transport COPII Vesicle Coating Vesicle Tethering	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Vesicle-mediated Transport COPII Vesicle Coating Vesicle Tethering
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		Palmitic Acid Myristic acid S-palmitoyl-L-cysteine
Diseases
GWAS		Glaucoma (primary open-angle) ( 33627673) Intraocular pressure ( 30054594)	Carotid intima media thickness (mean) ( 31801372) Hair color ( 26926045)
Interacting Genes		8 interacting genes: APP CDC45 LIG4 PLEKHF2 TRAPPC2 TRAPPC2B TRAPPC2L TRAPPC6A	27 interacting genes: APP BLZF1 BSDC1 C11orf68 CEP57L1 GPANK1 LCN2 LHX2 LMO3 MEI4 MEOX1 MEOX2 POLR2G RABEP1 REL REPS1 SSX2 SSX2B TCF4 TRAPPC3 TRAPPC3L TRAPPC6A TRIP6 TUBB3 UBC YPEL3 ZBTB42
Entrez ID		27095	51693
HPRD ID		11644	13711
Ensembl ID		ENSG00000054116	ENSG00000167515
Uniprot IDs		A0A087WWM0 A0A087WYS5 O43617	A0A0B4J294 H3BQQ8 H3BUK6 Q9UL33
PDB IDs		1SZ7 2C0J 2CFH 3KXC
Enriched GO Terms of Interacting Partners?		TRAPPIII Protein Complex TRAPP Complex COPII Vesicle Coating Vesicle Tethering Vesicle Coating TRAPPII Protein Complex Vesicle Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Transport Vesicle-mediated Transport Protein-containing Complex Assembly Golgi Vesicle Transport Protein-containing Complex Organization Cellular Localization Endoplasmic Reticulum Establishment Of Localization In Cell Cellular Component Assembly Perinuclear Region Of Cytoplasm Organelle Organization Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Establishment Of Integrated Proviral Latency Mitotic DNA Replication Preinitiation Complex Assembly Endoplasmic Reticulum-Golgi Intermediate Compartment Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Establishment Of Viral Latency DNA Replication Preinitiation Complex PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization DNA Ligase (ATP) Activity DNA Ligase IV Complex DNA Ligase Activity DNA Replication Preinitiation Complex Assembly Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling	TRAPP Complex Somite Specification Golgi Vesicle Transport Cis-Golgi Network Membrane TRAPPIII Protein Complex Segment Specification Somite Development
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