LAMP3 and SOX2-OT

		LAMP3	SOX2-OT
Description		lysosomal associated membrane protein 3	SOX2 overlapping transcript
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Plasma Membrane Cell Surface Endomembrane System Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Vesicle Perinuclear Region Of Cytoplasm Alveolar Lamellar Body Membrane
	Molecular Function
	Biological Process	Adaptive Immune Response Immune System Process Regulation Of Autophagy Positive Regulation Of Gene Expression Response To Interferon-alpha Symbiont Entry Into Host Cell Establishment Of Protein Localization To Organelle Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Viral Life Cycle
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Cutaneous leishmaniasis ( 32830257) Parkinson's disease ( 21292315 21738487 28011712) Subjective response to lithium treatment ( 26503763)	Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms) ( 32595297) Bipolar disorder and eating disorder ( 26433762) Eating disorder in bipolar disorder ( 26433762) Hallux valgus ( 32131869) Night sleep phenotypes ( 27126917) Schizophrenia ( 29483656) Self-reported risk-taking behaviour ( 30271922)
Interacting Genes		2 interacting genes: SGTB SOX2-OT	2 interacting genes: LAMP3 SIRT1
Entrez ID		27074	347689
HPRD ID		12062
Ensembl ID		ENSG00000078081	ENSG00000242808
Uniprot IDs		Q9UQV4
PDB IDs		4AKM
Enriched GO Terms of Interacting Partners?		TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Protein Targeting To ER Protein Heterooligomerization Establishment Of Protein Localization To Endoplasmic Reticulum Hsp70 Protein Binding Protein Targeting To Membrane Protein-folding Chaperone Binding	NAD-dependent Protein Lysine Delactylase Activity Regulation Of Proteasomal Protein Catabolic Process NAD-dependent Protein Decrotonylase Activity Regulation Of Cellular Response To Testosterone Stimulus Histone H4K12 Deacetylase Activity, Hydrolytic Mechanism Behavioral Response To Starvation Negative Regulation Of Peptidyl-lysine Acetylation Histone H4K16 Deacetylase Activity, NAD-dependent Negative Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Histone H3K9 Deacetylase Activity, NAD-dependent Maintenance Of Nucleus Location Histone Decrotonylase Activity, NAD-dependent Histone H3K14 Deacetylase Activity, NAD-dependent NAD-dependent Protein-lysine Depropionylase Activity Negative Regulation Of Cellular Response To Testosterone Stimulus Negative Regulation Of Prostaglandin Biosynthetic Process Histone H3K Deacetylase Activity Protein Depropionylation Positive Regulation Of Macrophage Apoptotic Process ENoSc Complex Positive Regulation Of CAMP-dependent Protein Kinase Activity Alveolar Lamellar Body Membrane Negative Regulation Of Protein Acetylation Negative Regulation Of Triglyceride Biosynthetic Process Triglyceride Mobilization Pyrimidine Dimer Repair By Nucleotide-excision Repair Regulation Of Protein Catabolic Process HLH Domain Binding Regulation Of Autophagy Regulation Of Proteolysis Histone Deacetylase Activity, NAD-dependent Regulation Of CAMP-dependent Protein Kinase Activity RDNA Heterochromatin Keratin Filament Binding RDNA Heterochromatin Formation Regulation Of Endodeoxyribonuclease Activity Stress-induced Premature Senescence NAD-dependent Protein Lysine Deacetylase Activity Ovulation From Ovarian Follicle Regulation Of Bile Acid Biosynthetic Process Pyrimidine Dimer Repair Regulation Of Transcription By Glucose Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Single Strand Break Repair Subtelomeric Heterochromatin Formation Chromatin Silencing Complex Response To Peptide Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore UV-damage Excision Repair Deacetylase Activity
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