GFRA3 and ARTN

Number of citations of the paper that reports this interaction (PubMedID 9883723)
0

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		GFRA3	ARTN
Description		GDNF family receptor alpha 3	artemin
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GO Annotations	Cellular Component	Cytosol Plasma Membrane External Side Of Plasma Membrane Membrane Extrinsic Component Of Membrane Receptor Complex Side Of Membrane	Extracellular Region Extracellular Space
	Molecular Function	Signaling Receptor Binding Protein Binding Axon Guidance Receptor Activity Glial Cell-derived Neurotrophic Factor Receptor Activity Signaling Receptor Activity	Signaling Receptor Binding Protein Binding Growth Factor Activity Glial Cell-derived Neurotrophic Factor Receptor Binding Receptor Tyrosine Kinase Binding
	Biological Process	Neuron Migration Signal Transduction Nervous System Development Axon Guidance Peripheral Nervous System Development Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Sympathetic Nervous System Development Neuron Development	Signal Transduction Nervous System Development Neuroblast Proliferation Axon Guidance Peripheral Nervous System Development Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Induction Of Positive Chemotaxis Peyer's Patch Morphogenesis Lymphocyte Migration Into Lymphoid Organs
Pathways		RAF/MAP kinase cascade RET signaling	NCAM1 interactions RAF/MAP kinase cascade RET signaling
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Autism spectrum disorder or schizophrenia ( 28540026) Immune reponse to smallpox (secreted IL-12p40) ( 22610502) QT interval ( 24952745) Schizophrenia ( 25056061)	Autism spectrum disorder or schizophrenia ( 28540026) Tea consumption ( 31046077)
Interacting Genes		2 interacting genes: ARTN COL6A3	5 interacting genes: DIO1 GFRA3 GOLM1 LDB1 TUBGCP3
Entrez ID		2676	9048
HPRD ID		10420	04863
Ensembl ID		ENSG00000146013	ENSG00000117407
Uniprot IDs		O60609	Q5T4W7
PDB IDs		2GH0 6Q2S	2ASK 2GH0 2GYR 2GYZ 6Q2S
Enriched GO Terms of Interacting Partners?		Collagen Type VI Trimer Glial Cell-derived Neurotrophic Factor Receptor Binding Peyer's Patch Morphogenesis Lymphocyte Migration Into Lymphoid Organs Induction Of Positive Chemotaxis Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Positive Regulation Of Positive Chemotaxis Peripheral Nervous System Development Extracellular Matrix Structural Constituent Conferring Tensile Strength Neuroblast Proliferation Extracellular Space Lymphocyte Migration Receptor Tyrosine Kinase Binding Neuron Apoptotic Process Extracellular Region Peptidase Inhibitor Activity Muscle Organ Development Sarcolemma Muscle Structure Development Collagen Trimer Serine-type Endopeptidase Inhibitor Activity Extracellular Vesicle Response To Monosaccharide Response To Glucose Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Neural Precursor Cell Proliferation Positive Regulation Of Chemotaxis Mononuclear Cell Migration Response To UV Response To Carbohydrate Growth Factor Activity
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