DAOA and MYO16

		DAOA	MYO16
Description		D-amino acid oxidase activator	myosin XVI
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm Plasma Membrane Myosin Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding ATP Binding Protein Phosphatase Binding Actin Filament Binding
	Biological Process	Positive Regulation Of Protein Catabolic Process D-amino Acid Metabolic Process	Negative Regulation Of Cell Population Proliferation Cerebellum Development Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Neuron Projection Morphogenesis Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585) Bipolar disorder and schizophrenia ( 20889312) Obesity-related traits ( 23251661) Periodontitis (DPAL) ( 24024966) Visceral fat ( 22589738)	Alzheimer's disease ( 30636644) Alzheimer's disease (cognitive decline) ( 23535033) Blood pressure ( 22763476) Chronotype ( 30696823) Colorectal cancer ( 29228715) Dental caries ( 23064961) Eosinophil count ( 32888494) Femur bone mineral density x serum urate levels interaction ( 34046847) Ferritin levels ( 33491795) Lung function (FEV1/FVC) ( 30804560) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494) Nose size ( 27182965) Obesity-related traits ( 23251661) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Presence of antiphospholipid antibodies ( 23509613) Red blood cell count ( 27863252 32888494) Red cell distribution width ( 32888494) Resting-state electroencephalogram vigilance ( 29703947) Seasonality ( 25562672) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		3 interacting genes: ARGLU1 DAO MYO16	7 interacting genes: CYFIP1 DAOA NCKAP1 NRXN1 PIK3R1 PPP1CA PPP1CC
Entrez ID		267012	23026
HPRD ID		07591	14795
Ensembl ID		ENSG00000182346	ENSG00000041515
Uniprot IDs		A2T115 P59103	F8W883 Q9Y6X6
PDB IDs
Enriched GO Terms of Interacting Partners?		D-serine Catabolic Process Glycine Oxidase Activity D-amino-acid Dehydrogenase Activity D-alanine Catabolic Process D-serine Metabolic Process D-amino Acid Catabolic Process D-amino-acid Oxidase Activity D-amino Acid Metabolic Process Neutrophil-mediated Killing Of Gram-negative Bacterium L-proline Catabolic Process L-leucine Metabolic Process Proline Metabolic Process Dopamine Biosynthetic Process Neutrophil-mediated Killing Of Bacterium Catecholamine Biosynthetic Process Pre-mRNA Binding Neutrophil Mediated Immunity Branched-chain Amino Acid Metabolic Process Digestion Amine Biosynthetic Process Biogenic Amine Biosynthetic Process Dopamine Metabolic Process Killing By Host Of Symbiont Cells Biological Process Involved In Interaction With Symbiont FAD Binding Presynaptic Active Zone Catecholamine Metabolic Process Peroxisomal Matrix Cytoskeletal Motor Activity Myosin Complex Cerebellum Development Glutamine Family Amino Acid Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Biogenic Amine Metabolic Process Negative Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Alternative MRNA Splicing, Via Spliceosome	Positive Regulation Of Lamellipodium Assembly Regulation Of Lamellipodium Assembly Positive Regulation Of Lamellipodium Organization Regulation Of Cell Projection Assembly Regulation Of Lamellipodium Organization Postsynapse PTW/PP1 Phosphatase Complex Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation SCAR Complex Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Actin Nucleation Positive Regulation Of Cellular Component Organization Positive Regulation Of Cellular Component Biogenesis Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Rac Protein Signal Transduction Photoperiodism Entrainment Of Circadian Clock Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Protein Stabilization Presynapse Lamellipodium Assembly Regulation Of Actin Nucleation Regulation Of Actin Filament Organization Lamellipodium Organization Regulation Of Filopodium Assembly Intracellular Signaling Cassette Response To Light Stimulus Glycogen Metabolic Process Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Stability Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cell Projection Organization Regulation Of Actin Filament-based Process Circadian Regulation Of Gene Expression Energy Reserve Metabolic Process Phosphatase Activity Polysaccharide Metabolic Process Positive Regulation Of Presynaptic Active Zone Assembly Positive Regulation Of Presynapse Assembly Positive Regulation Of CAMP-mediated Signaling Protein-containing Complex Assembly Involved In Synapse Maturation Focal Adhesion Positive Regulation Of Protein Localization To Membrane Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity
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