RGL4 and RALB

Number of citations of the paper that reports this interaction (PubMedID 12874025)
0

Data Source:
HPRD (in vitro)

		RGL4	RALB
Description		ral guanine nucleotide dissociation stimulator like 4	RAS like proto-oncogene B
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cytoplasmic Vesicle	Plasma Membrane Membrane Midbody Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Ubiquitin Protein Ligase Binding ATPase Binding
	Biological Process	Small GTPase-mediated Signal Transduction Ras Protein Signal Transduction	Regulation Of Exocyst Assembly Apoptotic Process Signal Transduction Ras Protein Signal Transduction Receptor Internalization Positive Regulation Of Innate Immune Response Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Division Regulation Of Exocyst Localization Positive Regulation Of Autophagosome Assembly
Pathways			p38MAPK events
Drugs
Diseases
GWAS			Breast size ( 27182965) Intraocular pressure ( 29617998) Mean platelet volume ( 27863252 32888494) Metabolite levels ( 23823483) Platelet count ( 27863252 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		4 interacting genes: HRAS RALA RALB RAP1A	8 interacting genes: CALM1 CXCR4 INCA1 PLCD1 RALBP1 REPS1 REPS2 RGL4
Entrez ID		266747	5899
HPRD ID		11528	01550
Ensembl ID		ENSG00000159496	ENSG00000144118
Uniprot IDs		Q3ZCN2 Q8IZJ4	P11234
PDB IDs			2KE5 2KWI 6ZQT 6ZRN
Enriched GO Terms of Interacting Partners?		GDP Binding G Protein Activity Small GTPase-mediated Signal Transduction GTPase Activity GTP Binding Ras Protein Signal Transduction Intracellular Signaling Cassette Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Protein Localization To Synapse Positive Regulation Of Cellular Component Organization Vesicle-mediated Transport Regulation Of Receptor Localization To Synapse Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Positive Regulation Of Cell Projection Organization Positive Regulation Of Signal Transduction Endocytosis Hydrolase Activity Nucleotide Binding Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cell Communication Intracellular Signal Transduction Positive Regulation Of Signaling Receptor Internalization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway ATPase Binding Import Into Cell Positive Regulation Of Immune Response Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Regulation Of Exocyst Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Cellular Component Organization GTPase Complex Edg-2 Lysophosphatidic Acid Receptor Binding Regulation Of Exocyst Localization Response To Antineoplastic Agent Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Localization To Membrane Receptor-mediated Endocytosis Regulation Of Immune Response Phospholipase C Activator Activity Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Exocytosis Positive Regulation Of Immune System Process Exocytosis Regulation Of Signal Transduction Regulation Of Cell Projection Assembly Regulation Of Organelle Organization	Endocytosis Intracellular Signaling Cassette Import Into Cell Calcium Ion Binding Signal Transduction Intracellular Signal Transduction Plasma Membrane C-X-C Motif Chemokine 12 Receptor Activity Doxorubicin Transport Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway Vesicle-mediated Transport Mitochondrion-endoplasmic Reticulum Membrane Tethering Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Calcium-mediated Signaling Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Autophagosome Membrane Docking Spindle Pole Phosphatidylinositol Phospholipase C Activity Anion Binding Phospholipase C/protein Kinase C Signal Transduction CXCL12-activated CXCR4 Signaling Pathway Myosin Light Chain Binding Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway C-X-C Chemokine Receptor CXCR4 Signaling Pathway Negative Regulation Of Voltage-gated Calcium Channel Activity Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway C-X-C Chemokine Receptor Activity ABC-type Glutathione S-conjugate Transporter Activity Protein-macromolecule Adaptor Activity Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
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