BLOC1S1 and PELP1

Number of citations of the paper that reports this interaction (PubMedID 12639951)
0

Data Source:
BioGRID (two hybrid)

		BLOC1S1	PELP1
Description		biogenesis of lysosomal organelles complex 1 subunit 1	proline, glutamate and leucine rich protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosome Lysosomal Membrane Early Endosome Cytosol Membrane BLOC-1 Complex Cytoplasmic Side Of Lysosomal Membrane BORC Complex Axon Cytoplasm	Euchromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane MLL1 Complex
	Molecular Function	Protein Binding Transferase Activity Protein-lysine-acetyltransferase Activity	Chromatin Binding RNA Binding Protein Binding SUMO Binding
	Biological Process	Anterograde Axonal Transport Aerobic Respiration Endosomal Transport Peptidyl-lysine Acetylation Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Regulation Of Endosome Size Platelet Dense Granule Organization Regulation Of Lysosome Size Organelle Transport Along Microtubule	RRNA Processing Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Estrogen Stimulus
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Major pathway of rRNA processing in the nucleolus and cytosol PTK6 Expression
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Eosinophil count ( 29403010)
Interacting Genes		18 interacting genes: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 DCTN2 FBXO44 HGS MAGEB4 MTA1 NOTCH1 PBX2 PELP1 PTN SNAPC5 SNAPIN USHBP1	28 interacting genes: AR BAG6 BCAS3 BLOC1S1 CREBBP EP300 ESR1 ESR2 H1-1 H2AC20 H2BC21 H3-3A H4C1 HGS LAS1L NFKB1 NR3C1 PTEN RB1 SENP3 SMAD9 SNCA SRC STAT3 SUMO2 TOM1L1 TP53 USP7
Entrez ID		2647	27043
HPRD ID		03263	10144
Ensembl ID		ENSG00000135441	ENSG00000141456
Uniprot IDs		P78537	B4DEX7 B4DR36 C9JFV4 E7EV54 Q8IZL8
PDB IDs			7UWF 8FL2 8FL3 8FL4
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport BLOC-1 Complex Axo-dendritic Transport Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Anterograde Axonal Transport Vesicle Transport Along Microtubule Establishment Of Vesicle Localization Vesicle Cytoskeletal Trafficking Vesicle Localization Axon Cytoplasm Axonal Transport Organelle Transport Along Microtubule Transport Along Microtubule Neuron Projection Development Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Establishment Of Organelle Localization Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Melanosome Localization Pigment Granule Localization Vesicle Organization Plasma Membrane Bounded Cell Projection Organization Microtubule-based Movement Microvesicle Endosome To Melanosome Transport Organelle Localization Cell Projection Organization Microtubule-based Process Cellular Localization Establishment Of Localization In Cell Intracellular Transport Secretion Of Lysosomal Enzymes Pigmentation Positive Regulation Of Pigment Cell Differentiation Regulation Of Lysosome Size BORC Complex Positive Regulation Of Developmental Pigmentation Regulation Of Endosome Size Negative Regulation Of Long-term Synaptic Potentiation Regulation Of Stem Cell Differentiation Cytoplasmic Side Of Lysosomal Membrane Regulation Of Developmental Pigmentation Developmental Pigmentation Chromatin Binding Rhythmic Process Regulation Of Vesicle Size	Transcription Coactivator Binding Negative Regulation Of Macromolecule Metabolic Process Chromatin Organization Negative Regulation Of Metabolic Process Estrogen Response Element Binding Positive Regulation Of Transcription By RNA Polymerase II Chromatin Transcription Regulator Complex Chromatin Remodeling Peptidyl-lysine Acetylation Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of MiRNA Metabolic Process Nucleoplasm Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Nucleus Intracellular Signal Transduction Nuclear Receptor Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Small Molecule Metabolic Process Cellular Response To Hormone Stimulus Regulation Of Primary Metabolic Process Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Stability Steroid Binding Regulation Of MiRNA Transcription Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway DNA Binding Enzyme Binding Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Positive Regulation Of RNA Metabolic Process Regulation Of Phosphorus Metabolic Process Protein Acetylation Structural Constituent Of Chromatin Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Response To Hormone Negative Regulation Of Biosynthetic Process
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