DRC4 and ZBTB22

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DRC4	ZBTB22
Description		dynein regulatory complex subunit 4	zinc finger and BTB domain containing 22
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Microtubule Plasma Membrane Cilium Axoneme Microtubule Cytoskeleton Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection 9+2 Motile Cilium	Chromatin Nucleus
	Molecular Function	Protein Binding Microtubule Binding Small GTPase Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Microtubule Cytoskeleton Organization Epithelial Cilium Movement Involved In Extracellular Fluid Movement Determination Of Left/right Symmetry Brain Development Intracellular Protein Localization Negative Regulation Of Cell Population Proliferation Flagellated Sperm Motility Axoneme Assembly Positive Regulation Of Smoothened Signaling Pathway Cell Motility Establishment Of Localization In Cell Cilium Movement Involved In Cell Motility Positive Regulation Of Protein Localization To Cilium	Regulation Of Transcription By RNA Polymerase II
Pathways		Activation of SMO
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Walking pace ( 33128006)
Interacting Genes		110 interacting genes: ARL6IP1 BCAR3 BORCS6 BYSL C1orf35 CARD10 CARD9 CBFA2T3 CCDC125 CCDC146 CCDC6 CCHCR1 CCNG1 CDC37 CDR2 CEP70 CFAP53 CINP CKS1B COG6 CPSF7 CRYBB1 CT45A1 CWF19L2 CYSRT1 DAXX DDX17 DISC1 DMAP1 EAF1 EHHADH EIF1AD ERCC1 EVI5L FAM161A FAM161B FHL2 GADD45GIP1 GCC1 GEM GOLGA2 GPRASP3 GRIPAP1 GSTA4 HEXIM2 HOMER3 HOMEZ HOXA1 HSF2BP IGFBP6 KDM1A KRT14 KRT15 KRT16 L3MBTL2 L3MBTL3 LASP1 LHX3 LMO1 LMO2 LZTS1 MAD1L1 MFAP1 MID2 MRFAP1L1 NDOR1 NKAPD1 PLK4 PNKP PNMA5 POLR1C POTEB3 PPFIA1 PRDM14 PRMT5 PRPF18 RALBP1 RBAK RINT1 RUBCN SCNM1 SKIL SORBS3 SP7 SPATA18 SPG21 STAC3 TCEA2 THAP1 TNFAIP3 TRAF2 TRAF5 TRIM41 TRIM54 TSFM TSGA10IP TXLNA TXLNB USHBP1 YES1 YJU2 ZBTB22 ZBTB26 ZBTB39 ZNF212 ZNF250 ZNF572 ZNF620 ZNF629 ZNF792	16 interacting genes: AP4M1 CCDC13 DNAJA3 DRC4 FXR2 GABARAPL1 GATA1 MCRS1 MEMO1 MLLT6 PIN1 RBM39 TCEA2 UBQLN4 VAPA VAPB
Entrez ID		2622	9278
HPRD ID		05533	15761
Ensembl ID		ENSG00000141013	ENSG00000236104
Uniprot IDs		A0A087WZT7 A0A384MR00 B7Z1U9 O95995	A0A1U9X8V3 O15209
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Zinc Ion Binding Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling	FFAT Motif Binding COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Endoplasmic Reticulum Localization Host-mediated Activation Of Viral Genome Replication Host-mediated Perturbation Of Viral Genome Replication Host-mediated Suppression Of Viral Genome Replication Organelle Organization Ciliary Basal Body Centriolar Satellite Viral Release From Host Cell Endoplasmic Reticulum Exit Site Vesicle Budding From Membrane Protein-membrane Adaptor Activity Host-mediated Activation Of Viral Process Beta-tubulin Binding Cis-trans Isomerase Activity
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