KIFBP and PLEKHF1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KIFBP	PLEKHF1
Description		kinesin family binding protein	pleckstrin homology and FYVE domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytoskeleton	Nucleus Cytoplasm Lysosome Lysosomal Membrane Endosome Early Endosome Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Kinesin Binding Protein Sequestering Activity	Protein Binding Zinc Ion Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding Metal Ion Binding Phosphatidylinositol-4-phosphate Binding
	Biological Process	Microtubule Cytoskeleton Organization In Utero Embryonic Development Nervous System Development Transport Along Microtubule Central Nervous System Projection Neuron Axonogenesis Cell Differentiation Mitochondrion Transport Along Microtubule Neuron Projection Maintenance	Apoptotic Process Endosome Organization Endosome To Lysosome Transport Positive Regulation Of Autophagy Vesicle Organization Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases		Goldberg-Shprintzen megacolon syndrome; Goldberg-Shprintzen syndrome (GOSHS) Polymicrogyria; Bilateral frontal polymicrogyria (BFP); Bilateral frontoparietal polymicrogyria (BFPP); Bilateral perisylvian polymicrogyria (BPP); Bilateral parasagittal parieto-occipital polymicrogyria (BPOP); Bilateral generalised polymicrogyria (BGP); Unilateral Polymicrogyria (ULP)
GWAS			Body mass index ( 26426971)
Interacting Genes		11 interacting genes: ATXN2 CEP76 DOK2 DPEP1 EXOSC2 HBP1 PLEKHF1 RGR TERF1 ZNF638 ZNF670	7 interacting genes: CAVIN2 CHIC2 KIFBP L3MBTL3 NPM2 TNFAIP8 TNNT1
Entrez ID		26128	79156
HPRD ID		13848	15146
Ensembl ID		ENSG00000198954	ENSG00000166289
Uniprot IDs		Q96EK5	B4DWN9 Q96S99
PDB IDs		6ZPG 6ZPH 7RSI 7RSQ 7RYP 7RYQ
Enriched GO Terms of Interacting Partners?		Lactam Catabolic Process Antibiotic Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Leukotriene D4 Catabolic Process GPI Anchor Binding Beta-lactamase Activity Glutathione Catabolic Process Modified Amino Acid Binding Metallodipeptidase Activity Photoreceptor Activity Regulation Of Establishment Of Protein Localization To Chromosome Nuclear Telomere Cap Complex Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Telomere Localization Shelterin Complex Meiotic Telomere Clustering Telomeric D-loop Disassembly Ankyrin Repeat Binding Double-stranded Telomeric DNA Binding Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) 7S RNA Binding TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance Nuclear Polyadenylation-dependent RRNA Catabolic Process U4 SnRNA 3'-end Processing CUT Catabolic Process Poly(A)-dependent SnoRNA 3'-end Processing	Slow-twitch Skeletal Muscle Fiber Contraction Troponin T Binding Oocyte Differentiation Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Methylation-dependent Protein Binding
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