ERC2 and PPFIA4

Number of citations of the paper that reports this interaction (PubMedID 12923177)
0

Data Source:
BioGRID (two hybrid, pull down, two hybrid)
HPRD (in vitro, two hybrid)

		ERC2	PPFIA4
Description		ELKS/RAB6-interacting/CAST family member 2	PPFI scaffold protein A4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Growth Cone Presynaptic Membrane Cell Projection Synapse Presynaptic Active Zone Presynapse Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse GABA-ergic Synapse	Cytoplasm Cytosol Cell Surface Synapse Presynaptic Active Zone
	Molecular Function	Protein Binding Structural Constituent Of Presynaptic Active Zone	Protein Binding
	Biological Process	Synaptic Vesicle Priming Maintenance Of Presynaptic Active Zone Structure Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion	Synapse Organization
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Adult body size ( 32376654) Alcohol dependence ( 24166409) Bipolar disorder and schizophrenia ( 21057379) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 26955885) Cortical surface area (MOSTest) ( 32665545) Daytime sleep phenotypes ( 27126917) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549 28869591) Hip bone size ( 31053729) Hip circumference adjusted for BMI ( 34021172) Hip geometry ( 17903296) Intertrochanteric region size ( 31053729) Lateral thalamic nuclei volume ( 34006833) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Morning vs. evening chronotype ( 26955885 27494321) Night sleep phenotypes ( 27126917) Periodontitis (Mean PAL) ( 24024966) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Sense of smell ( 26632684) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tourette syndrome ( 30818990) Trochanter size ( 31053729)	Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Atrial fibrillation ( 28416822 29892015 30061737) Early onset atrial fibrillation ( 28460022)
Interacting Genes		10 interacting genes: BSN HNF1B MYB NRIP1 PCLO PPFIA1 PPFIA2 PPFIA3 PPFIA4 RIMS1	6 interacting genes: AGTPBP1 CAST DNAJC5 ERC2 GIT1 NCOA2
Entrez ID		26059	8497
HPRD ID		10810	16012
Ensembl ID		ENSG00000187672	ENSG00000143847
Uniprot IDs		H7C4G9 O15083	A0A8J8YUZ5 B3KN22 B4DIS5 O75335
PDB IDs
Enriched GO Terms of Interacting Partners?		Presynaptic Active Zone Synapse Organization Cell Junction Organization Maintenance Of Synapse Structure Structural Constituent Of Presynaptic Active Zone Maintenance Of Presynaptic Active Zone Structure Cell Junction Maintenance Presynaptic Active Zone Organization Cellular Component Maintenance Cytoskeleton Of Presynaptic Active Zone Synaptic Vesicle Exocytosis Presynaptic Active Zone Assembly Signal Release Organelle Localization Synapse Synaptic Vesicle Docking Presynaptic Active Zone Cytoplasmic Component Vesicle-mediated Transport In Synapse Synaptic Vesicle Clustering Regulated Exocytosis Vesicle Localization Secretion By Cell Presynapse Organization Axon Modulation Of Chemical Synaptic Transmission Secretion Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Exocytosis Organelle Glutamatergic Synapse Regulation Of Secretion By Cell Vesicle Docking Involved In Exocytosis Regulation Of Secretion Insulin Secretion Postsynaptic Density Regulation Of Synaptic Vesicle Exocytosis Mesonephric Duct Formation Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Mesonephric Nephron Morphogenesis Ureteric Bud Elongation Pronephric Nephron Tubule Development Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Ovarian Follicle Rupture Structural Constituent Of Presynapse Vesicle Docking Epididymosome Protein Localization To Synapse Peptide Hormone Secretion Peptide Secretion Organelle Localization By Membrane Tethering	Presynaptic Active Zone Organization Locomotory Behavior Maintenance Of Synapse Structure Presynapse Cell Junction Maintenance Cellular Component Maintenance Calcium-dependent Cysteine-type Endopeptidase Inhibitor Activity Negative Regulation Of ARF Protein Signal Transduction Anterograde Axonal Transport Of Mitochondrion GABA-ergic Synapse Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion Regulation Of Vesicle-mediated Transport Structural Constituent Of Postsynaptic Specialization Cellular Response To Thyroglobulin Triiodothyronine Retrograde Axonal Transport Of Mitochondrion C-terminal Protein Deglutamylation Growth Cone Protein Deglutamylation Protein Side Chain Deglutamylation Neuron Development Response To Thyroglobulin Triiodothyronine Negative Regulation Of Type B Pancreatic Cell Apoptotic Process RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Aryl Hydrocarbon Receptor Binding Structural Constituent Of Presynaptic Active Zone Maintenance Of Presynaptic Active Zone Structure Intramembranous Ossification Positive Regulation Of Microtubule Nucleation Motor Learning ATP-dependent Protein Binding Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Chromaffin Granule Membrane Synapse Organization Positive Regulation Of Receptor Catabolic Process Maintenance Of Postsynaptic Specialization Structure Negative Regulation Of Inflammatory Response To Wounding Cytoplasm Locomotor Rhythm Peroxisome Proliferator Activated Receptor Signaling Pathway Regulation Of Small Molecule Metabolic Process Positive Regulation Of Adipose Tissue Development Peptidyl-glutamic Acid Modification Cerebellar Purkinje Cell Layer Development Axonal Transport Of Mitochondrion Cerebellar Purkinje Cell Differentiation Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Presynaptic Active Zone Cytoplasmic Component Immunological Synapse Formation Dendritic Spine Development Regulation Of Inflammatory Response To Wounding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?