VIRMA and HBM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VIRMA	HBM
Description		vir like m6A methyltransferase associated	hemoglobin subunit mu
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body Nuclear Speck RNA N6-methyladenosine Methyltransferase Complex	Hemoglobin Complex Haptoglobin-hemoglobin Complex
	Molecular Function	RNA Binding Protein Binding	Oxygen Carrier Activity Protein Binding Oxygen Binding Heme Binding Metal Ion Binding
	Biological Process	MRNA Processing RNA Splicing	Oxygen Transport Erythrocyte Development
Pathways
Drugs
Diseases
GWAS			Body mass index ( 26426971) Glycated hemoglobin levels ( 31213470) Hemoglobin ( 32888494) Hemoglobin A1c levels ( 31217584) Hemoglobin levels ( 26366553) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 28453575 27863252 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		4 interacting genes: HBM PIN1 RNF10 USP7	6 interacting genes: HBB HBD HBE1 HBG2 HBZ VIRMA
Entrez ID		25962	3042
HPRD ID		10889
Ensembl ID		ENSG00000164944	ENSG00000206177
Uniprot IDs		Q69YN4	Q6B0K9
PDB IDs		7VF2 7VF5 7YG4
Enriched GO Terms of Interacting Partners?		Hemoglobin Complex Haptoglobin-hemoglobin Complex Mitogen-activated Protein Kinase Kinase Binding GTPase Activating Protein Binding Protein Stabilization Ubiquitin Ligase Activator Activity Phosphoserine Residue Binding Regulation Of Protein Catabolic Process Protein Peptidyl-prolyl Isomerization Regulation Of Protein Stability Phosphothreonine Residue Binding Negative Regulation Of Catabolic Process Cis-trans Isomerase Activity Negative Regulation Of Protein Catabolic Process Regulation Of Establishment Of Protein Localization To Chromosome Monoubiquitinated Protein Deubiquitination Regulation Of Establishment Of Protein Localization To Telomere DNA Alkylation Repair Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Retrograde Transport, Endosome To Golgi Transcription-coupled Nucleotide-excision Repair Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Negative Regulation Of Schwann Cell Proliferation Extrinsic Component Of Postsynaptic Density Membrane Oxygen Carrier Activity Protein Modification Process Regulation Of Telomere Capping Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Oxygen Transport Negative Regulation Of Glial Cell Proliferation Negative Regulation Of Gluconeogenesis K48-linked Deubiquitinase Activity Positive Regulation Of Myelination Microtubule Polymerization Negative Regulation Of Amyloid-beta Formation Deubiquitinase Activity Oxygen Binding Negative Regulation Of Amyloid Precursor Protein Catabolic Process Protein Targeting To Mitochondrion Postsynaptic Cytosol Negative Regulation Of SMAD Protein Signal Transduction Glutamatergic Synapse Negative Regulation Of Protein Metabolic Process Erythrocyte Development Protein Ubiquitination	Hemoglobin Complex Haptoglobin-hemoglobin Complex Oxygen Carrier Activity Carbon Dioxide Transport Oxygen Transport Hemoglobin Alpha Binding One-carbon Compound Transport Oxygen Binding Erythrocyte Development Myeloid Cell Development Heme Binding Hemopoiesis Blood Microparticle Cell Development Cellular Developmental Process Haptoglobin Binding Nitric Oxide Transport Hemoglobin Binding Metal Ion Binding RNA N6-methyladenosine Methyltransferase Complex Hydrogen Peroxide Catabolic Process Endocytic Vesicle Lumen Erythrocyte Maturation Peroxidase Activity Hydrogen Peroxide Metabolic Process Developmental Process
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