GALR1 and SNAPC5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GALR1	SNAPC5
Description		galanin receptor 1	small nuclear RNA activating complex polypeptide 5
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GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Nucleoplasm Nucleolus Nuclear Body
	Molecular Function	G Protein-coupled Receptor Activity Galanin Receptor Activity Protein Binding Peptide Hormone Binding Neuropeptide Binding	RNA Polymerase III General Transcription Initiation Factor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cortisol Secretion	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		A body shape index ( 34021172) Appendicular lean mass ( 33097823) Blood osmolality (transformed sodium) ( 28360221) DHEAS levels ( 34748635) Height ( 31562340) Metabolite levels ( 31628463) Obesity-related traits ( 23251661) Smoking initiation (ever regular vs never regular) ( 31089300) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		3 interacting genes: CD226 GAL SNAPC5	43 interacting genes: AMOT ARHGEF38 BATF BFSP2 BLOC1S1 BRCC3 CBY2 CCDC196 CDCA8 CREB5 CREBBP CYTH1 CYTH4 DDIT3 EMILIN1 FAM9C GALR1 GORAB GRIPAP1 HMG20B ITGB3BP JUN LMO2 MBD3L1 MCRS1 MYF5 NDEL1 NMI NOL4 NUDT10 NUP62 POLR2J RNF4 S100Z SNAPC1 SNAPC4 STMN4 TRAPPC2 TRAPPC2B TXLNB ZNF177 ZNF559-ZNF177 ZNRD2
Entrez ID		2587	10302
HPRD ID		02657	16183
Ensembl ID		ENSG00000166573	ENSG00000174446
Uniprot IDs		P47211	O75971
PDB IDs		7WQ3 7XJJ	7ZWC 7ZWD 7ZX7 7ZX8 7ZXE
Enriched GO Terms of Interacting Partners?		Type 2 Galanin Receptor Binding Type 3 Galanin Receptor Binding Positive Regulation Of Large Conductance Calcium-activated Potassium Channel Activity Type 1 Galanin Receptor Binding Galanin Receptor Binding Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity Regulation Of Natural Killer Cell Cytokine Production Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Positive Regulation Of Mast Cell Activation Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Natural Killer Cell Cytokine Production Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Protein Kinase A Signaling Positive Regulation Of Timing Of Catagen Positive Regulation Of Hair Follicle Development Positive Regulation Of Cortisol Secretion Galanin Receptor Activity Regulation Of Glucocorticoid Metabolic Process Regulation Of Timing Of Catagen SnRNA Transcription Parental Behavior Positive Regulation Of Immune Response To Tumor Cell Regulation Of Mast Cell Activation Positive Regulation Of T Cell Receptor Signaling Pathway Regulation Of Hair Follicle Development Regulation Of Cell Activation Response To Immobilization Stress Positive Regulation Of Cation Channel Activity Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Response To Tumor Cell Neuropeptide Hormone Activity Regulation Of Hair Cycle Transcription By RNA Polymerase III Reproductive Behavior Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Regulation Of Hormone Metabolic Process Positive Regulation Of Natural Killer Cell Mediated Immunity RNA Polymerase II General Transcription Initiation Factor Activity Positive Regulation Of Immunoglobulin Mediated Immune Response Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Transporter Activity Natural Killer Cell Mediated Immunity Insulin Secretion	SnRNA-activating Protein Complex Peptidyl-lysine Acetylation Protein Binding Integrated Stress Response Signaling RNA Polymerase II Transcription Regulator Complex CAMP Response Element Binding TRAPPII Protein Complex TRAPPIII Protein Complex SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity Positive Regulation Of Mitotic Cytokinesis Centrosome Separation Mitotic Centrosome Separation SnRNA Transcription Regulation Of Mitotic Cytokinesis
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