ARMC8 and GID8

Number of citations of the paper that reports this interaction (PubMedID 36621627)
59

Data Source:
BioGRID (pull down)

		ARMC8	GID8
Description		armadillo repeat containing 8	GID complex subunit 8 homolog
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol GID Complex Specific Granule Lumen Tertiary Granule Lumen	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Cell Junction
	Molecular Function	Protein Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Positive Regulation Of Cell Population Proliferation Wnt Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Neutrophil degranulation Regulation of pyruvate metabolism	Regulation of pyruvate metabolism
Drugs
Diseases
GWAS		A body shape index ( 34021172) Mean spheric corpuscular volume ( 32888494) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Appendicular lean mass ( 33097823) Monocyte count ( 32888494)
Interacting Genes		10 interacting genes: CIB3 CTNNA1 GID8 PKP1 PKP2 STX6 TCF12 TNNT1 USP25 ZMYND12	2 interacting genes: ARMC8 RANBP9
Entrez ID		25852	54994
HPRD ID		09992	12738
Ensembl ID		ENSG00000114098	ENSG00000101193
Uniprot IDs		B7Z637 Q8IUR7	Q9NWU2
PDB IDs		7NSC	7NSC
Enriched GO Terms of Interacting Partners?		Intermediate Filament Binding Intermediate Filament Bundle Assembly Desmosome Assembly Desmosome Organization Cell-cell Junction Assembly Cell-cell Junction Organization Desmosome Adherens Junction Cell Junction Intercalated Disc Cell Junction Assembly Cornified Envelope Maintenance Of Protein Localization At Cell Tip Slow-twitch Skeletal Muscle Fiber Contraction Cadherin Binding Intermediate Filament Organization Desmosome Maintenance Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Anchoring Junction Negative Regulation Of Integrin-mediated Signaling Pathway Cytoskeleton Organization Positive Regulation Of Cap-dependent Translational Initiation Synaptic Vesicle To Endosome Fusion Negative Regulation Of Interleukin-17-mediated Signaling Pathway Cell Junction Organization Maintenance Of Animal Organ Identity Troponin T Binding Cell-cell Adhesion Cellular Response To Indole-3-methanol Transepithelial Water Transport Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication Ubiquitin-like Protein Peptidase Activity Response To Indole-3-methanol Positive Regulation Of Cytoplasmic Translational Initiation Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Interleukin-17A-mediated Signaling Pathway Apical Junction Assembly Gap Junction Assembly Zonula Adherens Nuclear Stress Granule Intermediate Filament Ameloblast Differentiation Regulation Of Muscle Contraction Cell Tip Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Response To Gonadotropin-releasing Hormone Troponin Complex Transition Between Fast And Slow Fiber Negative Regulation Of ERAD Pathway	Ubiquitin Ligase Complex GID Complex
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