SNX33 and NAF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SNX33	NAF1
Description		sorting nexin 33	nuclear assembly factor 1 ribonucleoprotein
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle	Nucleus Nucleoplasm Sno(s)RNA-containing Ribonucleoprotein Complex Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Protein Binding Phosphatidylinositol Binding Identical Protein Binding	RNA Binding Protein Binding Identical Protein Binding Telomerase RNA Binding
	Biological Process	Mitotic Cell Cycle Mitotic Cytokinesis Intracellular Protein Transport Endocytosis Endosome Organization Positive Regulation Of Catabolic Process Protein Transport Endosomal Transport Protein Import Cleavage Furrow Formation Macropinocytosis Negative Regulation Of Endocytosis Positive Regulation Of Membrane Protein Ectodomain Proteolysis Cell Division Plasma Membrane Tubulation Negative Regulation Of Protein Localization To Cell Surface Positive Regulation Of Protein Localization To Cell Surface	SnoRNA Guided RRNA Pseudouridine Synthesis Box H/ACA SnoRNP Assembly Pseudouridine Synthesis RRNA Processing Protein-RNA Complex Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Ribosome Biogenesis RNA Stabilization Telomerase RNA Stabilization Telomerase RNA Localization To Cajal Body Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Telomerase Holoenzyme Complex Assembly
Pathways
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462)	Chronotype ( 30696823) Colorectal cancer ( 25023989) Daytime nap ( 33568662) Hair morphology ( 19896111) Leukocyte telomere length ( 31171785 32109421) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) TPE interval (recovery after exercise) ( 32386560)
Interacting Genes		8 interacting genes: ADAM15 DPPA4 FASLG FBXO7 NAA10 NAF1 PAK2 ZNF575	26 interacting genes: BOLL CSNK2A1 DAB1 ELOA FAM168A HERPUD2 KRTAP19-3 KRTAP19-7 KRTAP6-1 KRTAP6-2 MAGED1 MED31 MSX2 RAMAC RBFOX2 SCARNA13 SCARNA8 SH3RF1 SNORA74A SNX33 SORBS3 SS18L1 TENT5B TLE5 UBE2I YWHAE
Entrez ID		257364	92345
HPRD ID		11331	10054
Ensembl ID		ENSG00000173548	ENSG00000145414
Uniprot IDs		Q8WV41	Q96HR8
PDB IDs		4AKV	2EQN
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Phosphatidylserine Exposure On Apoptotic Cell Surface Protein-N-terminal-alanine Acetyltransferase Activity Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Protein-N-terminal-glutamate Acetyltransferase Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Box H/ACA SnoRNP Assembly Retinal Cell Programmed Cell Death Protein N-terminal-serine Acetyltransferase Activity Lewy Body Core SnoRNA Guided RRNA Pseudouridine Synthesis Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Phospholipid Translocation Cytoplasmic Vesicle Lumen Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Sister Chromatid Cohesion NatA Complex Negative Regulation Of Receptor Binding Response To Hypobaric Hypoxia Telomerase RNA Stabilization Regulation Of Extrinsic Apoptotic Signaling Pathway Inflammatory Cell Apoptotic Process Protein-N-terminal Amino-acid Acetyltransferase Activity Telomerase Holoenzyme Complex Assembly
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