C10orf67 and ACSF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C10orf67	ACSF2
Description		chromosome 10 open reading frame 67	acyl-CoA synthetase family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding	Nucleotide Binding Catalytic Activity Long-chain Fatty Acid-CoA Ligase Activity Protein Binding ATP Binding Ligase Activity Medium-chain Fatty Acid-CoA Ligase Activity
	Biological Process		Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process
Pathways			Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		Crohn's disease and sarcoidosis (combined) ( 18723019) Heel bone mineral density ( 30598549) Systemic lupus erythematosus ( 19838195)	Heel bone mineral density ( 30598549)
Interacting Genes		14 interacting genes: ACSF2 ALOX5 BCL2L1 BCL2L2 CACNB2 NOD2 ORMDL3 SEC22A SYT16 TMED8 TMEM14B TMEM19 TMEM208 TNF	19 interacting genes: AGTRAP APOA5 APOC1 ARL13B ARL6IP1 C10orf67 CLEC10A CMTM5 COQ9 CREB3 DGAT2L6 GPR152 MICOS13 RDH10 RHBDD2 SENP2 SIGLEC12 SYNGR3 USP40
Entrez ID		256815	80221
HPRD ID		12585	13380
Ensembl ID		ENSG00000179133	ENSG00000167107
Uniprot IDs		A0A6E2AE84 Q8IYJ2	B4DTB9 E9PF16 Q96CM8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Negative Regulation Of Vascular Wound Healing Negative Regulation Of Leukocyte Apoptotic Process Bcl-2 Family Protein Complex Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Vascular Wound Healing Extrinsic Apoptotic Signaling Pathway Regulation Of Membrane Lipid Metabolic Process Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Release Of Cytochrome C From Mitochondria Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Epithelial Cell Proliferation Mitochondrial Membrane Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Apoptotic Process Channel Activity Negative Regulation Of Programmed Cell Death Leukotriene A4 Biosynthetic Process Arachidonate 5-lipoxygenase Activity Negative Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Apoptotic Process In Bone Marrow Cell Negative Regulation Of Bile Acid Secretion Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Response To Gram-negative Bacterium Negative Regulation Of Branching Involved In Lung Morphogenesis Detection Of Muramyl Dipeptide Muramyl Dipeptide Binding Negative Regulation Of Endothelial Cell Proliferation Leukotriene A4 Metabolic Process Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Wound Healing Arachidonate 8(S)-lipoxygenase Activity Apoptotic Mitochondrial Changes Cellular Response To Ionizing Radiation Positive Regulation Of Interleukin-1 Production Chronic Inflammatory Response To Antigenic Stimulus Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Interleukin-8 Production Positive Regulation Of Fractalkine Production Positive Regulation Of Non-canonical NF-kappaB Signal Transduction	Phosphatidylcholine-sterol O-acyltransferase Activator Activity Very-low-density Lipoprotein Particle Clearance Acylglycerol Metabolic Process Chylomicron Neutral Lipid Metabolic Process Phospholipid Efflux Very-low-density Lipoprotein Particle High-density Lipoprotein Particle Regulation Of Ketone Metabolic Process Plasma Lipoprotein Particle Clearance Acylglycerol Homeostasis Protein-containing Complex Remodeling Lipoprotein Metabolic Process Phosphatidylcholine Binding Cholesterol Efflux Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Plasma Lipoprotein Particle Remodeling Negative Regulation Of Phosphatidylcholine Catabolic Process Endoplasmic Reticulum Membrane Positive Regulation Of Deacetylase Activity Isoprenoid Binding Primary Lung Bud Formation Positive Regulation Of Retinoic Acid Biosynthetic Process Regulation Of Lipid Biosynthetic Process Regulation Of Fatty Acid Biosynthetic Process Regulation Of Lipid Catabolic Process Triglyceride Metabolic Process Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Lipase Activator Activity Endoplasmic Reticulum Unfolded Protein Response Cholesterol Transport Regulation Of Phosphatidylcholine Catabolic Process Membrane Lipoprotein Particle Receptor Binding Lipoprotein Lipase Activator Activity Receptor Localization To Non-motile Cilium Acylglycerol Acyl-chain Remodeling Sterol Transport Alcohol Metabolic Process
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