CNIH2 and CD53

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CNIH2	CD53
Description		cornichon family AMPA receptor auxiliary protein 2	CD53 molecule
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane ER To Golgi Transport Vesicle Membrane Postsynaptic Density Membrane Dendrite AMPA Glutamate Receptor Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cell Projection Dendritic Spine Dendritic Shaft Synapse Postsynaptic Membrane	Immunological Synapse Plasma Membrane Cell-cell Junction Membrane Specific Granule Membrane Synapse Extracellular Exosome Anchoring Junction Tertiary Granule Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding	Protein Binding Identical Protein Binding Protein-membrane Adaptor Activity
	Biological Process	Vesicle-mediated Transport Synaptic Transmission, Glutamatergic Regulation Of AMPA Receptor Activity	Signal Transduction Receptor Clustering T Cell Receptor Signaling Pathway Positive Regulation Of Myoblast Fusion
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER	Neutrophil degranulation
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Insomnia ( 32332799) Urate levels ( 31578528)	Cytomegalovirus antibody response ( 21993531) Obesity-related traits ( 23251661)
Interacting Genes		8 interacting genes: CD53 CREB3L1 GORAB HIBADH SNCA TMEM14B TMEM200A TMPRSS2	80 interacting genes: AIG1 APOD ARL13B ASGR2 ATP6V0C BCL2L13 BIK BTN2A2 C1QL4 CD2 CD302 CD37 CD4 CD9 CLCN7 CLDN19 CLDN7 CLEC7A CNIH1 CNIH2 COL4A5 CREB3L1 CTXN3 CXCL16 CYBC1 ECE2 EFNA5 EMP1 ERG28 FAM209A GET1 GGT1 GIMAP5 GJA8 GPR108 GPR152 GPX8 IFITM3 IGFBP5 IL2 IL4 KIR3DL3 LAT LHFPL5 LPAR3 LSMEM1 MAL MS4A3 MUC1 NKG7 PLN PLP2 PMP22 PSCA RPRM SAR1A SERTM1 SLC35A1 SLC7A14 SMAGP SMIM3 SNORC ST6GAL2 STRIT1 STX2 TMEM128 TMEM140 TMEM218 TMEM229B TMEM237 TMEM60 TMEM86B TMEM97 TRAM1L1 TRARG1 TSPO2 UBIAD1 UPK1B VAMP5 VSTM1
Entrez ID		254263	963
HPRD ID		13078	01054
Ensembl ID		ENSG00000174871	ENSG00000143119
Uniprot IDs		Q6PI25	B4DQB5 P19397
PDB IDs		8SS2 8SS3 8SS4 8SS6 8SS7 8SSA 8SSB	6WVG
Enriched GO Terms of Interacting Partners?		Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission 3-hydroxyisobutyrate Dehydrogenase Activity	Membrane Plasma Membrane Membrane Raft Distribution Membrane Raft Localization Protein Binding Bleb Assembly Membrane Raft Polarization T Cell Activation Endomembrane System Membrane Raft Organization Endoplasmic Reticulum Membrane Defense Response To Protozoan Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
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