ALPP and PIGK

Number of citations of the paper that reports this interaction (PubMedID 12616539)
0

Data Source:
HPRD (in vitro, in vivo)

		ALPP	PIGK
Description		alkaline phosphatase, placental	phosphatidylinositol glycan anchor biosynthesis class K
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GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Side Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GPI-anchor Transamidase Complex
	Molecular Function	Magnesium Ion Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Phosphatase Activity Metal Ion Binding	GPI-anchor Transamidase Activity Protein Binding Peptidase Activity Transferase Activity GPI Anchor Binding
	Biological Process		GPI Anchor Biosynthetic Process Proteolysis Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis
Pathways		Intra-Golgi traffic	Attachment of GPI anchor to uPAR
Drugs		Calcium METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Diseases
GWAS		Blood protein levels ( 30072576) Height ( 19570815) Refractive error ( 32231278)	Chronotype ( 27494321 30696823) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		49 interacting genes: ADAMTSL4 ALPG CRCT1 CREB5 CXCL5 CYSRT1 FBXO34 GEMIN4 GPLD1 GSC2 HOXA1 IGFBP6 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP5-9 KRTAP9-3 LATS1 LCE1B LCE1C LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 MPHOSPH9 NBPF19 NLGN3 NOTCH2NLA NR4A3 NUFIP2 OTX1 PIGK POU4F2 RGS19 RGS20 SMCP TGM1 TUBA4A	3 interacting genes: ALPP GPAA1 PIGT
Entrez ID		250	10026
HPRD ID		01379	05474
Ensembl ID		ENSG00000163283	ENSG00000142892
Uniprot IDs		B2R7C7 P05187	Q92643
PDB IDs		1EW2 1ZEB 1ZED 1ZEF 2GLQ 3MK0 3MK1 3MK2	7W72 7WLD 8IMX 8IMY
Enriched GO Terms of Interacting Partners?		Keratinization Epidermis Development Tissue Development Intermediate Filament Keratin Filament Identical Protein Binding	GPI-anchor Transamidase Complex Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis GPI Anchor Binding GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Glycolipid Biosynthetic Process Glycolipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Metabolic Process Glycerophospholipid Biosynthetic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process GPI-anchor Transamidase Activity Glycerophospholipid Metabolic Process Alkaline Phosphatase Activity Protein Maturation Glycerolipid Metabolic Process Phospholipid Metabolic Process Protein Retention In ER Lumen Maintenance Of Protein Localization In Endoplasmic Reticulum Carbohydrate Derivative Biosynthetic Process Lipid Biosynthetic Process Organophosphate Biosynthetic Process Carbohydrate Derivative Metabolic Process Maintenance Of Protein Localization In Organelle Organophosphate Metabolic Process Maintenance Of Protein Location In Cell Maintenance Of Protein Location Endoplasmic Reticulum Membrane Lipid Metabolic Process Maintenance Of Location In Cell Phosphatase Activity Maintenance Of Location Phosphate-containing Compound Metabolic Process Neuron Apoptotic Process Side Of Membrane Endoplasmic Reticulum
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