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BCL2L13 and FUS
Number of citations of the paper that reports this interaction (PubMedID
24706805
)
34
Data Source:
BioGRID
(two hybrid)
BCL2L13
FUS
Description
BCL2 like 13
FUS RNA binding protein
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Mitochondrion
Membrane
Mitochondrial Membrane
Nucleus
Nucleoplasm
Cytoplasm
Glutamatergic Synapse
GABA-ergic Synapse
Presynaptic Cytosol
Postsynaptic Cytosol
Molecular Function
Protein Binding
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Nucleic Acid Binding
DNA Binding
Chromatin Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
RNA Binding
MRNA 3'-UTR Binding
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Metal Ion Binding
Molecular Condensate Scaffold Activity
Biological Process
Mitophagy
Oxidative Phosphorylation
Apoptotic Process
Mitochondrion Organization
Regulation Of Apoptotic Process
Fat Cell Differentiation
Canonical Glycolysis
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
RNA Splicing
Gene Expression
Regulation Of RNA Splicing
Positive Regulation Of DNA-templated Transcription
MRNA Stabilization
Protein Homooligomerization
Membraneless Organelle Assembly
Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Amyloid Fibril Formation
Pathways
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
Myxoid liposarcoma
Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS
Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma (
29551627
)
Eosinophil count (
32888494
)
Granulocyte count (
27863252
)
Hemoglobin levels (
32327693
)
Interleukin-10 levels (
22205395
)
Lymphocyte percentage of white cells (
32888494
)
Monocyte count (
32888494
)
Myeloid white cell count (
27863252
)
Neutrophil count (
27863252
32888494
)
Neutrophil percentage of white cells (
32888494
)
Sum neutrophil eosinophil counts (
27863252
)
White blood cell count (
32888494
)
Bipolar disorder (
31043756
)
Bipolar I disorder (
31043756
)
HDL cholesterol levels (
32203549
)
Interacting Genes
85 interacting genes:
ACP5
ADIPOQ
AGTRAP
AIG1
APOD
APP
AQP1
ARL6IP1
ARLN
BAZ2B
BCL9
BET1
CAMLG
CD53
CDC42
CDK5R1
CERS6
CLDN19
CRB3
DEFB127
ERG28
ERMP1
ETNK2
FAM210B
FUS
FXYD3
FZD7
GABARAPL2
GALNT2
GAST
GTF2F1
HMOX2
HNRNPK
IDI1
IL17RA
JAGN1
JPH4
LAT
LAYN
LPAR3
MAL
MGMT
MTNR1B
NDRG4
NETO2
NINJ2
NR2C2AP
NRBP1
PCBP1
PLLP
PLN
PLP1
PLPP4
PPT2
RPN2
SH3RF3
SLC30A8
SLC35A1
SLC35G5
SMARCD3
SMIM1
SPOCK1
SQLE
SRSF3
STX12
STX8
TM6SF2
TMEM128
TMEM14C
TMEM242
TMEM254
TMEM51
TMEM72
TMEM86A
TMEM86B
TMEM97
TMUB2
TNF
TNMD
TRARG1
TUBB
UBC
UPK1B
VAMP3
VAMP4
124 interacting genes:
ADAMTS9-AS2
AKT1
ARID1A
ATM
ATXN1L
BACH2
BCL2L13
CEBPA
CHEK2
CREBBP
CTNNB1
ESRRA
FNDC3B
GRIN1
GRIN2D
IL7R
ILF3
ISG15
KHDRBS3
MAX
MDH1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NKD2
OGT
PCDHA9
PDE4B
POLR2A
PRMT1
PSMB7
PTBP1
RELA
RXRA
SAFB2
SF1
SFPQ
SMARCB1
SMARCC1
SMARCC2
SMARCD1
SPI1
SRRM1
SRSF10
SRSF2
SRSF4
SRSF9
SS18
SUV39H1
TDRD3
THRA
UBQLN2
WBP4
YBX1
ZMYM2
Entrez ID
23786
2521
HPRD ID
09822
00660
Ensembl ID
ENSG00000099968
ENSG00000089280
Uniprot IDs
A0A087WTL4
A0A087WW80
A0A087WX97
A0A0A0MR90
A8K5Y4
B2RB43
B7Z238
B7Z737
E9PDD6
F2Z2C3
F6VJB4
Q9BXK5
A0AAQ5BIG2
P35637
Q13344
Q6IBQ5
PDB IDs
2LA6
2LCW
4FDD
4FQ3
5W3N
5XRR
5XSG
5YVG
5YVH
5YVI
6BWZ
6BXV
6BZP
6G99
6GBM
6KJ1
6KJ2
6KJ3
6KJ4
6SNJ
6XFM
7CYL
7VQQ
Enriched GO Terms of Interacting Partners
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Membrane
Endoplasmic Reticulum Membrane
Endoplasmic Reticulum
Localization Within Membrane
SNARE Complex
Cellular Localization
Response To Type II Interferon
Structural Constituent Of Myelin Sheath
Protein Binding
Regulation Of Transport
Alkenylglycerophosphocholine Hydrolase Activity
Cellular Response To Type II Interferon
SNAP Receptor Activity
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Organelle Fusion
Regulation Of Cellular Localization
Phagocytic Vesicle
Membrane Raft
Regulation Of Chemokine Production
Protein Localization To Membrane
Protein Localization To Cell Periphery
Vesicle Fusion
Vesicle Organization
Organelle Membrane Fusion
Negative Regulation Of Blood Circulation
Vesicle Docking
Regulation Of Establishment Of Protein Localization
Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Regulation Of Protein Transport
Response To Cytokine
Protein Localization To Plasma Membrane
Response To Peptide
Positive Regulation Of Chemokine Production
G Protein-coupled Receptor Signaling Pathway Involved In Heart Process
Membrane Raft Distribution
Establishment Of Protein Localization To Membrane
Recycling Endosome
Organelle Localization By Membrane Tethering
Membrane Raft Localization
MiRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Regulatory NcRNA-mediated Gene Silencing
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
MRNA 3'-UTR Binding
Regulation Of Gene Expression
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Regulation Of Metabolic Process
Negative Regulation Of Translation
Extracellular Vesicle
MRNA Destabilization
RNA Destabilization
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Regulation Of MRNA Metabolic Process
Positive Regulation Of MRNA Catabolic Process
Negative Regulation Of Cell Migration
Negative Regulation Of Developmental Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Cell Motility
Regulation Of Translation
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of Angiogenesis
Negative Regulation Of Locomotion
Regulation Of Vasculature Development
Negative Regulation Of Cytokine Production
Positive Regulation Of MRNA Metabolic Process
Regulation Of MRNA Stability
Regulation Of RNA Stability
Negative Regulation Of Multicellular Organismal Process
Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Signal Transduction
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Multicellular Organismal Development
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Endothelial Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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