LDOC1 and GNL3L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LDOC1	GNL3L
Description		LDOC1 regulator of NFKB signaling	G protein nucleolar 3 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Telomerase Holoenzyme Complex Nucleolus Cytosol Membrane
	Molecular Function	Protein Binding	Nucleotide Binding RNA Binding Protein Binding GTP Binding
	Biological Process	Maternal Placenta Development Negative Regulation Of Cell Population Proliferation Maternal Process Involved In Parturition Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	Positive Regulation Of Protein-containing Complex Assembly Negative Regulation Of Protein Ubiquitination Regulation Of Protein Stability Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Protein Sumoylation Ribosome Biogenesis Positive Regulation Of Protein Localization To Chromosome, Telomeric Region
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 31562322)
Interacting Genes		106 interacting genes: AATF ABLIM1 AEBP2 AIRIM AP1M1 AQP1 ATF4 ATP6V1G1 BARD1 BEX2 BYSL CCDC33 CCDC85B CDC5L CEBPE CFAP53 CTNNBL1 DPF2 DPPA4 ENKD1 FAM107A FAM110A FAM161A FAM193B FAM50B FAM90A1 FCHSD2 FOSL1 FXR2 GADD45GIP1 GNL3L GPANK1 HAUS1 HDAC4 HGS HOXB5 HOXC8 IKZF3 IKZF5 INPP1 IQCB1 JRK KRT15 KRT18 LATS1 LENG1 LMO2 LNX1 MBD3 MEAF6 MFAP1 MSGN1 MYC MZF1 NOD2 NRIP1 NXF1 PLEKHF2 POLL PPP1R18 PRPF18 PRPF31 PSMA1 PSMF1 RAB29 RALBP1 RASSF10 RIBC1 RNF6 RPP25 SCNM1 SDCBP SETD5 SH2D4A SMARCB1 SMARCD1 SUDS3 TASOR2 TBC1D7 TCEANC TEAD4 THAP7 TLE5 TMSB4XP1 TNNT1 TSGA10IP TSNAX TTC23 UBTFL1 UTP14A WDR25 WT1 ZBTB16 ZBTB24 ZFP1 ZGPAT ZNF124 ZNF250 ZNF408 ZNF564 ZNF587 ZNF629 ZNF648 ZNF688 ZNF774 ZNF835	16 interacting genes: ADRB2 ALAS1 CTBP1 DYNLL1 GOLGA2 HMBOX1 HSF2BP KPNA1 LDOC1 LZTS2 MTUS2 PRKAR1B ROPN1 TERF1 TFIP11 TRIM54
Entrez ID		23641	54552
HPRD ID		02322	06514
Ensembl ID		ENSG00000182195	ENSG00000130119
Uniprot IDs		O95751	Q05DU1 Q9NVN8
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleoplasm DNA-binding Transcription Factor Activity Nuclear Speck Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Stem Cell Population Maintenance Zinc Ion Binding Positive Regulation Of Stem Cell Population Maintenance DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Spindle Pole DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Chromatin NBAF Complex Positive Regulation Of RNA Biosynthetic Process Centrosome Positive Regulation Of DNA-templated Transcription Chromatin Organization Cytoskeleton Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Protein-DNA Complex Disassembly Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Regulation Of Nucleotide-excision Repair Ribosome Biogenesis SWI/SNF Complex Positive Regulation Of Transcription By RNA Polymerase I Spliceosomal Complex	Microtubule Double-stranded Telomeric DNA Binding Identical Protein Binding Microtubule Binding Telomere Maintenance Mitotic Spindle Negative Regulation Of DNA Metabolic Process Negative Regulation Of DNA Replication RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomerase Telomere Organization Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of CAMP/PKA Signal Transduction Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Mini Excitatory Postsynaptic Potential Organelle Organization Reproductive Process Microtubule-based Process Regulation Of DNA Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere DNA Metabolic Process Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Chromosome, Telomeric Region Microtubule Associated Complex Telomere-telomerase Complex Assembly Primary Ureteric Bud Growth Cytoplasm Microtubule Cytoskeleton Beta2-adrenergic Receptor Activity Establishment Of Localization In Cell Developmental Process 5-aminolevulinate Synthase Activity Response To Nickel Cation Cytoskeleton Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Spliceosomal Complex Disassembly Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Satellite Cell Activation Involved In Skeletal Muscle Regeneration Deoxyribonuclease Inhibitor Activity Centrosome Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity
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