SSBP2 and PDE8B

		SSBP2	PDE8B
Description		single stranded DNA binding protein 2	phosphodiesterase 8B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol
	Molecular Function	DNA Binding Single-stranded DNA Binding Protein Binding	3',5'-cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-AMP Phosphodiesterase Activity Phosphoric Diester Hydrolase Activity Hydrolase Activity Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Behavioral Fear Response CAMP Catabolic Process Signal Transduction Visual Learning Operant Conditioning Negative Regulation Of Insulin Secretion Neuromuscular Process Controlling Balance Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Steroid Hormone Biosynthetic Process Negative Regulation Of CAMP/PKA Signal Transduction
Pathways			G alpha (s) signalling events
Drugs			Caffeine Trapidil
Diseases			Pigmented micronodular adrenocortical disease (PPNAD)
GWAS		Adult body size ( 32376654) Anorexia nervosa ( 21079607) Bipolar disorder ( 31043756 33263727 34002096) Glioblastoma ( 22472174) HDL cholesterol levels in HIV infection ( 33109212) Plateletcrit ( 32888494)	Autoimmune thyroid disease ( 32581359) Caudate nucleus volume ( 21502949) Chronotype ( 30696823) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Hyperthyroidism ( 30367059) Hypothyroidism ( 27182965 30367059 22493691) Medication use (thyroid preparations) ( 31015401) Serum thyroid-stimulating hormone levels ( 25436638) Sjögren's syndrome ( 28076899) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335 32769997 18514160)
Interacting Genes		7 interacting genes: CDK6 EWSR1 IL36RN LDB1 LDB2 PIN1 TOM1
Entrez ID		23635	8622
HPRD ID		09577	04546
Ensembl ID		ENSG00000145687	ENSG00000113231
Uniprot IDs		A0A087X159 P81877	A0A2R8Y4E6 B3KN77 O95263
PDB IDs		6IWV 6TYD 8HIB
Enriched GO Terms of Interacting Partners?		LIM Domain Binding Transcription Coregulator Activity Regulation Of Metabolic Process Epithelial Structure Maintenance Negative Regulation Of Metabolic Process Regulation Of Erythrocyte Differentiation Cyclin D2-CDK6 Complex Cis-trans Isomerase Activity Cell Leading Edge Hair Follicle Development Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding Establishment Of Protein Localization To Mitochondrion Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Somatic Stem Cell Population Maintenance Hair Cycle Process Myosin VI Binding Negative Regulation Of Biosynthetic Process	Pigment Granule Aggregation In Cell Center Primary Palate Development BBSome Pigment Granule Localization Establishment Of Melanosome Localization Digestive Tract Morphogenesis Melanosome Localization Melanosome Transport Pigment Granule Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?