ZFYVE26 and CEP44

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		ZFYVE26	CEP44
Description		zinc finger FYVE-type containing 26	centrosomal protein 44
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Early Endosome Late Endosome Centrosome Cytoskeleton Midbody	Spindle Pole Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Midbody Ciliary Basal Body
	Molecular Function	Protein Binding Zinc Ion Binding Lipid Binding Protein Kinase Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding	Protein Binding Microtubule Binding
	Biological Process	Mitotic Cytokinesis Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Damage Response Lysosome Organization Regulation Of Cytokinesis Cell Division Autophagosome Organization	Centrosome Cycle Centriole Replication Centriole-centriole Cohesion
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Asthma ( 31959851) Asthma (childhood onset) ( 31036433)
Interacting Genes		36 interacting genes: ALAS1 ASB15 CBY2 CCDC125 CCDC136 CEP44 CFTR GOLGA2 GPRASP2 HMBOX1 HNRNPC HOOK2 KRT15 KRT27 KRT34 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAGED1 MDFI PLEKHF2 PNMA1 PNMA5 PPP1R16A PRDM6 SPAG5 SSX2IP TADA2A TCEANC TDO2 TFIP11 TRAF1 TTC23 USHBP1 USP20	56 interacting genes: ABI2 ABI3 ANKRD11 AQP1 BEND7 BFSP2 BLOC1S6 BYSL CAB39 CBY2 CCDC116 CCDC146 CCDC185 CDC23 CENPP CEP57L1 CHIC2 DCTN2 DHX57 DIP2A ERAL1 FAM161A FAM74A4 FXR2 GNG11 GPM6A H2AP HAUS1 ING5 KIAA0930 LINC02363 LMO1 LRRFIP1 MAPK9 MCRS1 MLLT6 MRFAP1L1 NAA10 PLEKHF2 POC1B POLR3C POP5 PSMD3 RBM15 RECK RNF8 SCNM1 TCEA2 TRIM41 TSGA10 TXLNA ZFYVE26 ZNF250 ZNF417 ZNF587 ZNF688
Entrez ID		23503	80817
HPRD ID		15734	13885
Ensembl ID		ENSG00000072121	ENSG00000164118
Uniprot IDs		Q68DK2	Q9C0F1
PDB IDs			7PT5
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Identical Protein Binding Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Centrosome Cycle
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