LARP4B and PITRM1

		LARP4B	PITRM1
Description		La ribonucleoprotein 4B	pitrilysin metallopeptidase 1
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GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane	Mitochondrion Mitochondrial Matrix
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding	Metalloendopeptidase Activity Protein Binding Enzyme Activator Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Regulation Of Translation Positive Regulation Of Translation Positive Regulation Of 3'-UTR-mediated MRNA Stabilization	Proteolysis Protein Targeting To Mitochondrion Protein Processing
Pathways			Mitochondrial protein import
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252 32888494) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Chronotype ( 30696823) Estimated glomerular filtration rate ( 31015462 31451708 31152163) Estimated glomerular filtration rate in non-diabetics ( 31451708) Femur bone mineral density x serum urate levels interaction ( 34046847) Neutrophil percentage of granulocytes ( 27863252) Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016) Prostate cancer (early onset) ( 29892016) Reticulocyte fraction of red cells ( 32888494) Sum eosinophil basophil counts ( 27863252) White blood cell count (basophil) ( 27863252)	Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Metabolite levels ( 23823483) Scalp hair shape ( 26926045)
Interacting Genes		16 interacting genes: ADARB2 ATXN1L C1QTNF9 DIP2C DMRTB1 IDI1 IDI2 IDI2-AS1 LINC00200 MAGED1 OGT PABPC1 PITRM1 RBPMS TUBB8 WDR37	9 interacting genes: BID DPT IDI1 LARP4B MFN2 PNLIPRP1 S100A7 SOCS6 WDR77
Entrez ID		23185	10531
HPRD ID		13787	07142
Ensembl ID		ENSG00000107929	ENSG00000107959
Uniprot IDs		Q92615	A0A0A0MRX9 A0A7I2V397 Q5JRX3
PDB IDs		3PTH	4L3T 4NGE 4RPU 6XOS 6XOT 6XOU 6XOV 6XOW
Enriched GO Terms of Interacting Partners?		Dimethylallyl Diphosphate Biosynthetic Process Isopentenyl-diphosphate Delta-isomerase Activity Intramolecular Oxidoreductase Activity Isopentenyl Diphosphate Biosynthetic Process Isopentenyl Diphosphate Metabolic Process Isoprenoid Biosynthetic Process Cholesterol Biosynthetic Process Sterol Biosynthetic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly	Protein Targeting To Mitochondrion
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