MAPK8IP3 and KLC2

Number of citations of the paper that reports this interaction (PubMedID 11106729)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		MAPK8IP3	KLC2
Description		mitogen-activated protein kinase 8 interacting protein 3	kinesin light chain 2
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Axon Dendrite Growth Cone Cytoplasmic Vesicle Cell Projection Cell Body Perinuclear Region Of Cytoplasm Axon Cytoplasm	Nucleoplasm Cytoplasm Mitochondrion Lysosome Lysosomal Membrane Cytosol Cytoskeleton Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex
	Molecular Function	MAP-kinase Scaffold Activity Protein Binding JUN Kinase Binding Kinesin Binding Signaling Receptor Complex Adaptor Activity	Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	MAPK Cascade Vesicle-mediated Transport Axon Regeneration Negative Regulation Of Apoptotic Process Regulation Of JNK Cascade Positive Regulation Of JNK Cascade Protein Stabilization Axon Development Anterograde Axonal Protein Transport	Microtubule-based Movement Lysosome Localization
Pathways			MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Intraocular pressure ( 29617998)	Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)
Interacting Genes		28 interacting genes: ARL4D BTG3 CASP3 FXR1 KLC1 KLC2 LDLRAP1 MAP2K1 MAP2K4 MAP2K7 MAP3K11 MAP3K5 MAPK10 MAPK8 MAPK8IP1 MAPK8IP2 MAPK9 NRIP1 PTK2 RAD51 RAD51D RAF1 RIC8A SRC TLR2 TLR4 TLR9 ZNF575	19 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 DYNC1I1 KIF2A KLC1 LRRK2 MAPK8IP3 PACS1 PIK3R3 PRC1 RUSC2 S100A8 TRIB1 YWHAG YWHAQ YWHAZ
Entrez ID		23162	64837
HPRD ID		12014	13917
Ensembl ID		ENSG00000138834	ENSG00000174996
Uniprot IDs		A0A087WYG2 B7ZMF3 E9PFH7 Q9UPT6	Q9H0B6
PDB IDs		4PXJ 8PR2 8PR3 8PR4 8PTK	3CEQ 3EDT
Enriched GO Terms of Interacting Partners?		JNK Cascade MAPK Cascade Fc Receptor Signaling Pathway Cellular Senescence Protein Kinase Activity Intracellular Signaling Cassette Fc-epsilon Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Kinase Activity Positive Regulation Of MAPK Cascade Protein Serine Kinase Activity Regulation Of JNK Cascade JUN Kinase Activity Positive Regulation Of Intracellular Signal Transduction MAP Kinase Kinase Activity Protein Serine/threonine Kinase Activity Regulation Of Apoptotic Process Cytoplasm MAP Kinase Activity Positive Regulation Of JNK Cascade Regulation Of Programmed Cell Death Intracellular Signal Transduction Response To Wounding Positive Regulation Of Signal Transduction Regulation Of MAPK Cascade Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade ATP Binding Nucleotide Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Signal Complex Assembly Positive Regulation Of Protein Metabolic Process Regulation Of Intracellular Signal Transduction Cellular Response To Oxygen-containing Compound JUN Kinase Binding Kinesin Binding MAP-kinase Scaffold Activity Protein Phosphorylation Detection Of Molecule Of Bacterial Origin Regulation Of Immune Response Protein Tyrosine Kinase Activity Phosphorylation Mitogen-activated Protein Kinase Kinase Kinase Binding Regulation Of Apoptotic Signaling Pathway JUN Kinase Kinase Activity Positive Regulation Of Cellular Response To Macrophage Colony-stimulating Factor Stimulus Regulation Of Immune System Process Glial Cell Development	Kinesin Binding Cytosol Microtubule Binding Growth Cone Transmembrane Transporter Binding Cytoskeletal Motor Activity Cellular Response To Manganese Ion Microtubule-based Movement RAGE Receptor Binding Response To Manganese Ion Golgi-associated Vesicle Cellular Response To Catecholamine Stimulus Microtubule-based Process Response To Catecholamine Intracellular Signaling Cassette Regulation Of Synapse Organization Intracellular Signal Transduction Regulation Of Synapse Maturation Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Toll-like Receptor Signaling Pathway Regulation Of JNK Cascade Regulation Of Immune System Process Positive Regulation Of Inflammatory Response Regulation Of Response To Calcium Ion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Transport Along Microtubule Amylin Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Neuron Differentiation Positive Regulation Of Toll Signaling Pathway Regulation Of Apoptotic Process Regulation Of CAMP/PKA Signal Transduction Regulation Of Programmed Cell Death Cytoplasm Regulation Of MAPK Cascade Microtubule Vesicle Spindle Pole Kinesin Complex Spindle Microtubule S100A8 Complex Cellular Response To Starvation Regulation Of Protein Stability Protein Sequestering Activity X11-like Protein Binding Signaling Receptor Complex Adaptor Activity Cellular Response To Curcumin Caveola Neck
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