FCHO1 and LGALS14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FCHO1	LGALS14
Description		FCH and mu domain containing endocytic adaptor 1	galectin 14
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Membrane Clathrin-coated Vesicle Postsynaptic Endocytic Zone	Nucleus Nucleoplasm
	Molecular Function	Protein Binding AP-2 Adaptor Complex Binding	Protein Binding Carbohydrate Binding
	Biological Process	Endocytosis Clathrin Coat Assembly T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Activation Clathrin-dependent Endocytosis	Apoptotic Process
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Basophil count ( 32888494) Coronary artery disease ( 29212778) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Monocyte percentage of white cells ( 32888494) Myocardial infarction ( 33532862)	Sum eosinophil basophil counts ( 27863252)
Interacting Genes		52 interacting genes: ACVR1 APP BYSL CCDC13 CFTR CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15L1 EXOSC5 FBXL7 GDF15 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688	47 interacting genes: ADAMTSL4 AJUBA BANP BLZF1 C1QTNF2 CFTR COG6 CRLF3 DDIT4L DOK6 FCHO1 FLACC1 FLNA GFAP IKZF3 IL16 JRK KRT19 KRT35 LNX1 LNX2 MEI4 MID2 NFKBID PCBD2 PICK1 POF1B PPM1J REL RIMBP3C SDCBP2 SH3GLB2 SPAG5 STAT5B TARS3 TBC1D25 TCF4 TEKT1 TEPSIN TNR TRIM23 TRIM27 VIM ZBTB8A ZNF438 ZNF655 ZNF71
Entrez ID		23149	56891
HPRD ID		16887	06268
Ensembl ID		ENSG00000130475	ENSG00000006659
Uniprot IDs		A0A0C3SFZ9 A0A8V8TMX9 A0A8V8TNC3 A0A8V8TPM7 B7ZAZ3 M0QYA9 O14526	Q8TCE9
PDB IDs		7OHI	6K2Y 6K2Z
Enriched GO Terms of Interacting Partners?		Intermediate Filament Clathrin-coated Pit Protein Targeting To Vacuole Involved In Autophagy Endosome To Plasma Membrane Transport Vesicle Regulation Of SMAD Protein Signal Transduction Low-density Lipoprotein Particle Receptor Binding Cytosol Positive Regulation Of Aggrephagy Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Enamel Mineralization Clathrin Coat Of Coated Pit Keratin Filament Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Regulation Of Vesicle-mediated Transport Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of SMAD Protein Signal Transduction Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Binding Regulation Of Growth Receptor Metabolic Process SMAD Binding Negative Regulation Of Protein Localization Protein Targeting To Vacuole Negative Regulation Of Growth	Identical Protein Binding Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?