FLII and LRRFIP2

Number of citations of the paper that reports this interaction (PubMedID 10366446)
0

Data Source:
HPRD (two hybrid)

		FLII	LRRFIP2
Description		FLII actin remodeling protein	LRR binding FLII interacting protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Podosome Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Brush Border Focal Adhesion Actin Cytoskeleton Centriolar Satellite Cell Projection Anchoring Junction
	Molecular Function	Actin Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding	Protein Binding LRR Domain Binding
	Biological Process	Actin Polymerization Or Depolymerization Myofibril Assembly Sarcomere Organization Actin Filament Severing Barbed-end Actin Filament Capping	Regulation Of DNA-templated Transcription Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Femur bone mineral density x serum urate levels interaction ( 34046847) Subjective response to lithium treatment ( 26503763)
Interacting Genes		16 interacting genes: ACTB ACTL6A CARM1 DLST ESR1 GRIP1 LCOR LRRFIP1 LRRFIP2 MAPK7 MYD88 NCOA2 OPTN PRMT1 RNF34 TRAIP	5 interacting genes: ATPAF2 DNAJC19 FLII OGT TRANK1
Entrez ID		2314	9209
HPRD ID		02647	10061
Ensembl ID		ENSG00000177731	ENSG00000093167
Uniprot IDs		Q13045	A0A1S5UZ17 Q9Y608
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Nucleoplasm Nitric-oxide Synthase Regulator Activity Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Chromatin Remodeling Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Protein-arginine Omega-N Asymmetric Methyltransferase Activity Protein-arginine N-methyltransferase Activity Regulation Of RNA Metabolic Process Positive Regulation Of DNA Recombination Nucleus Intracellular Receptor Signaling Pathway Protein Methyltransferase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Brahma Complex Regulation Of Macromolecule Metabolic Process NpBAF Complex Regulation Of Double-strand Break Repair Via Homologous Recombination GBAF Complex Chromatin Organization RSC-type Complex Cellular Response To Oxygen-containing Compound Positive Regulation Of Double-strand Break Repair Regulation Of Gene Expression Positive Regulation Of Cell Population Proliferation Beta-catenin Binding Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of Signal Transduction Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of DNA Recombination Positive Regulation Of DNA Repair Signal Transduction NuA4 Histone Acetyltransferase Complex Regulation Of Nucleotide-excision Repair Regulation Of Double-strand Break Repair SWI/SNF Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Histone Methyltransferase Activity Protein-containing Complex Cellular Response To Estradiol Stimulus Negative Regulation Of Intracellular Signal Transduction Regulation Of G0 To G1 Transition Regulation Of Smooth Muscle Cell Apoptotic Process Regulation Of Signal Transduction Nucleosomal DNA Binding	Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein N-acetylglucosaminyltransferase Complex Non-canonical Inflammasome Complex Assembly Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Mitochondrial Proton-transporting ATP Synthase Complex Assembly Proton-transporting ATP Synthase Complex Assembly Matrix Side Of Mitochondrial Inner Membrane Inner Mitochondrial Membrane Protein Complex PAM Complex, Tim23 Associated Import Motor Regulation Of Cardiolipin Metabolic Process Membraneless Organelle Assembly Regulation Of Transcription By Glucose
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