TBC1D2B and TRDMT1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		TBC1D2B	TRDMT1
Description		TBC1 domain family member 2B	tRNA aspartic acid methyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Cytoplasmic Vesicle	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding	RNA Binding Methyltransferase Activity TRNA Methyltransferase Activity TRNA (cytidine-5-)-methyltransferase Activity Transferase Activity
	Biological Process	Endocytosis Regulation Of Cilium Assembly	TRNA Modification TRNA Processing TRNA Methylation Methylation TRNA Stabilization
Pathways			tRNA modification in the nucleus and cytosol
Drugs			Pentamidine S-adenosyl-L-homocysteine Glycerin
Diseases
GWAS		Diffusing capacity of carbon monoxide ( 30694715) Eyebrow thickness ( 26926045) Metabolite levels ( 23823483)	Aspartate aminotransferase levels ( 33547301) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Telomere length ( 24478790)
Interacting Genes		4 interacting genes: GABARAPL1 MAP1LC3A MTDH TRDMT1	14 interacting genes: APP COPS6 DDX24 EEF1A1 GBE1 LRIF1 NFRKB RBM48 SETDB1 SNRPD3 STX1A TBC1D2B UNC119 UTP14A
Entrez ID		23102	1787
HPRD ID		08310	16001
Ensembl ID		ENSG00000167202	ENSG00000107614
Uniprot IDs		B2RTQ2 Q9UPU7	B4DQZ2 O14717 Q6ICS7 Q7Z3E4
PDB IDs			1G55
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Mitophagy Autophagosome Maturation Autophagosome Membrane Autophagy Of Mitochondrion Autophagosome Autophagosome Assembly Autophagosome Organization Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy TRNA (cytidine-5-)-methyltransferase Activity Vacuole Organization Cellular Response To Starvation Cellular Response To Oxygen-glucose Deprivation Response To Starvation TRNA Methyltransferase Activity TRNA Stabilization Cellular Response To Nutrient Levels Autophagy Ubiquitin Protein Ligase Binding Response To Iron(II) Ion Intercellular Canaliculus Microtubule Tat Protein Binding Response To Oxygen-glucose Deprivation Glycophagy Autolysosome GABA Receptor Binding Response To Lead Ion Response To Nutrient Levels Glycogen Catabolic Process Cellular Response To Copper Ion Polysaccharide Catabolic Process SMAD Protein Signal Transduction P38MAPK Cascade Response To Iron Ion NF-kappaB Binding Response To Copper Ion TRNA Methylation Lipopolysaccharide-mediated Signaling Pathway Beta-tubulin Binding Organelle Assembly Organelle Membrane
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