ERC1 and CRIP1

		ERC1	CRIP1
Description		ELKS/RAB6-interacting/CAST family member 1	cysteine rich protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Podosome Cytoplasm Golgi Apparatus Centrosome Cytoskeleton Plasma Membrane IkappaB Kinase Complex Membrane Ciliary Basal Body Presynaptic Membrane Cell Projection Synapse Anchoring Junction Presynapse Presynaptic Active Zone Cytoplasmic Component	Cytoplasm
	Molecular Function	Protein Binding PDZ Domain Binding Small GTPase Binding Cadherin Binding Structural Constituent Of Presynaptic Active Zone	Zinc Ion Binding Peptide Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription I-kappaB Phosphorylation Protein Transport Retrograde Transport, Endosome To Golgi Maintenance Of Presynaptic Active Zone Structure Positive Regulation Of NF-kappaB Transcription Factor Activity	Immune Response Heart Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Zinc Ion Regulation Of Gene Expression Prostate Gland Stromal Morphogenesis Cellular Response To Antibiotic Cellular Response To UV-B
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms) ( 32595297) Body mass index ( 26426971) Femur bone mineral density x serum urate levels interaction ( 34046847) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420) Medial temporal lobe substructure volumes ( 32768867) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Monocyte percentage of white cells ( 32888494)
Interacting Genes		21 interacting genes: APP CD163 CRIP1 DNAJC5 DYRK1A FGF23 FPR2 GALNT8 GPRC5D IFFO1 ITSN2 MRTFB NCAPD2 PPFIA1 PRMT8 RAB6A RAB6B RIMS1 SRPK2 UBC YWHAG	7 interacting genes: AP2M1 ERC1 GPRASP1 HAP1 PIK3CA SH3GL3 STUB1
Entrez ID		23085	1396
HPRD ID		06181	00469
Ensembl ID		ENSG00000082805	ENSG00000213145
Uniprot IDs		G8JLD3 Q8IUD2 X6RLX0 X6RM00	P50238
PDB IDs
Enriched GO Terms of Interacting Partners?		Presynapse Endosome To Plasma Membrane Transport Vesicle Protein Localization To Golgi Membrane Vesicle-mediated Transport RAGE Receptor Binding Regulation Of Neuron Apoptotic Process Astrocyte Activation Positive Regulation Of Superoxide Anion Generation Myosin V Binding Positive Regulation Of Dendrite Extension Vesicle-mediated Transport In Synapse Regulation Of Modification Of Synaptic Structure Regulation Of Modification Of Postsynaptic Structure Regulation Of Superoxide Anion Generation Positive Regulation Of Monocyte Chemotaxis Protein Localization To Golgi Apparatus Regulation Of Superoxide Metabolic Process Microglial Cell Activation Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Monocyte Chemotaxis Leukocyte Activation Involved In Inflammatory Response Synaptic Vesicle Exocytosis Intra-Golgi Vesicle-mediated Transport Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Histone H3T45 Kinase Activity Peptidyl-cysteine Methylation Protein Methylation Positive Regulation Of Vitamin D 24-hydroxylase Activity Presynaptic Active Zone Positive Chemotaxis Regulation Of Cellular Component Organization Positive Regulation Of ERK1 And ERK2 Cascade Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Modulation Of Excitatory Postsynaptic Potential	Vesicle-mediated Transport Presynapse Positive Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Regulation Of Receptor-mediated Endocytosis Regulation Of Cellular Localization Endocytosis Intracellular Transport Regulation Of Vesicle-mediated Transport Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Cellular Component Biogenesis Response To Butyrate ERBB Signaling Pathway Cellular Response To Hydrostatic Pressure Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Brain-derived Neurotrophic Factor Binding Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Neurotrophin Production Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity G Protein-coupled Receptor Catabolic Process Negative Regulation Of Vascular Associated Smooth Muscle Contraction Positive Regulation Of Chaperone-mediated Protein Complex Assembly I-kappaB Phosphorylation Synaptic Vesicle Transmembrane Transporter Binding Import Into Cell Signal Sequence Binding Phosphatidylinositol 3-kinase Complex, Class IB Negative Regulation Of Clathrin-dependent Endocytosis Ubiquitin Conjugating Enzyme Complex Cellular Localization Enzyme-linked Receptor Protein Signaling Pathway Establishment Of Localization In Cell Regulation Of Protein Localization To Membrane Extrinsic Component Of Presynaptic Endocytic Zone Membrane Postsynaptic Endosome Hypothalamus Cell Differentiation Positive Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Synaptic Vesicle Recycling Postsynaptic Neurotransmitter Receptor Internalization Autosome Genomic Imprinting Response To Muscle Inactivity Phosphatidylinositol 3-kinase Complex 1-phosphatidylinositol-4-phosphate 3-kinase Activity Negative Regulation Of Fibroblast Apoptotic Process Regulation Of Macroautophagy 1-phosphatidylinositol-4,5-bisphosphate 3-kinase Activity Response To Hydrostatic Pressure Chaperone-mediated Autophagy TPR Domain Binding
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