GGA2 and CLINT1

Number of citations of the paper that reports this interaction (PubMedID 12429846)
46

Data Source:
HPRD (in vitro)

		GGA2	CLINT1
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 2	clathrin interactor 1
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GO Annotations	Cellular Component	Endosome Golgi Apparatus Trans-Golgi Network Endosome Membrane Membrane Clathrin-coated Vesicle Early Endosome Membrane	Nucleoplasm Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Endomembrane System Membrane Clathrin Vesicle Coat Clathrin-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding	Protein Binding Phospholipid Binding Lipid Binding Clathrin Binding Cadherin Binding
	Biological Process	Intracellular Protein Transport Golgi To Plasma Membrane Transport Protein Transport Vesicle-mediated Transport Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport	Endocytosis Clathrin Coat Assembly
Pathways		TBC/RABGAPs Amyloid fiber formation	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Diastolic blood pressure ( 27841878) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		43 interacting genes: ADRA2B AFTPH AP1G1 APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC ETS1 FBXO7 GGA1 GGA3 GOLGA2 GTPBP4 HGS HTT IGF2R JUN LRP3 M6PR MAP3K1 MEMO1 NPM1 PIN1 RABEP1 RABGEF1 RNF11 RTN4IP1 SORL1 SORT1 SPG21 STAB1 SYNRG TOLLIP TP53 TRIM23 VPS18 ZNF536	14 interacting genes: AP1G1 AP2A1 AP2B1 CALM1 CEBPA CLTC DNM1 EPS15 GDPD5 GGA1 GGA2 GGA3 JUN YWHAG
Entrez ID		23062	9685
HPRD ID		09347	06273
Ensembl ID		ENSG00000103365	ENSG00000113282
Uniprot IDs		Q9UJY4	A0A0S2Z4Y4 A0A0S2Z5H3 Q14677
PDB IDs		1MHQ	1XGW 2QY7 2V8S
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Intracellular Transport Early Endosome Endosome Cellular Localization Establishment Of Protein Localization Establishment Of Localization In Cell Protein Transport Intracellular Protein Transport Endocytosis Golgi Apparatus Lysosomal Transport Trans-Golgi Network Import Into Cell Intracellular Protein Localization Vacuolar Transport Clathrin-coated Vesicle Golgi Vesicle Transport Recycling Endosome Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Protein Targeting To Lysosome Protein Targeting Perinuclear Region Of Cytoplasm Establishment Of Protein Localization To Organelle Protein Targeting To Vacuole Protein-containing Complex Trans-Golgi Network Membrane Protein Localization To Lysosome Endosome Membrane Establishment Of Protein Localization To Vacuole Early Endosome Membrane Cytoplasmic Vesicle Cytosolic Transport Clathrin-coated Pit Retromer Complex Binding Golgi To Lysosome Transport Nuclear Envelope Lumen Lysosome Protein Localization To Organelle AP-1 Adaptor Complex Endosomal Transport Protein Localization To Vacuole Ubiquitin Binding Protein Transporter Activity Regulation Of Amyloid Precursor Protein Catabolic Process Trans-Golgi Network Transport Vesicle Golgi To Vacuole Transport Vesicle-mediated Transport To The Plasma Membrane Amyloid-beta Metabolic Process	Clathrin-coated Pit Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Clathrin Coat Assembly Clathrin-coated Vesicle Vesicle-mediated Transport In Synapse Endocytosis Postsynaptic Neurotransmitter Receptor Internalization Presynaptic Endocytosis Postsynaptic Endocytic Zone Cytosolic Transport Golgi Vesicle Transport AP-2 Adaptor Complex Intracellular Protein Transport Establishment Of Protein Localization Receptor-mediated Endocytosis Import Into Cell Trans-Golgi Network Receptor Internalization Clathrin Adaptor Activity Endolysosome Membrane Establishment Of Localization In Cell Protein Transport Clathrin-coated Endocytic Vesicle Intracellular Transport Ubiquitin Binding Intracellular Protein Localization Membrane Coat Protein Localization To Cell Surface Clathrin-dependent Endocytosis Golgi To Plasma Membrane Protein Transport Vesicle-mediated Transport To The Plasma Membrane Negative Regulation Of Hyaluronan Biosynthetic Process Synaptic Vesicle Endocytosis Cellular Localization Clathrin Coat Clathrin Coat Of Trans-Golgi Network Vesicle Regulation Of Hyaluronan Biosynthetic Process Clathrin Coat Of Coated Pit Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Protein-containing Complex Early Endosome Membrane Clathrin-coated Endocytic Vesicle Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Clathrin Adaptor Complex Endosomal Transport Golgi To Endosome Transport Small GTPase Binding Phosphatidylinositol Binding
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