KIN and MIR363

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		KIN	MIR363
Description		Kin17 DNA and RNA binding protein	microRNA 363
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Protein-containing Complex	Extracellular Space
	Molecular Function	DNA Binding Double-stranded DNA Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	DNA Replication DNA Repair DNA Recombination MRNA Processing DNA Damage Response	MiRNA-mediated Post-transcriptional Gene Silencing
Pathways		Protein methylation
Drugs
Diseases
GWAS		Asthma ( 31959851) Mean reticulocyte volume ( 32888494)
Interacting Genes		3 interacting genes: IL2RA MIR1-1 MIR363	94 interacting genes: ADARB1 APOBEC3B ATXN2L C1QBP CDC5L CELF1 CELF2 CHERP DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KIN LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PTCD3 PUF60 PURA PURB QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RTCA RTCB SAFB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		22944	574031
HPRD ID		03425
Ensembl ID		ENSG00000151657	ENSG00000284499
Uniprot IDs		O60870
PDB IDs		2CKK 2V1N 7ABH 7ABI 8I0P 9COJ
Enriched GO Terms of Interacting Partners?		Regulation Of T Cell Homeostatic Proliferation Interleukin-2 Receptor Complex Interleukin-2 Binding Interleukin-2 Receptor Activity Regulatory NcRNA-mediated Gene Silencing Reversible Differentiation Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Phenotypic Switching Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Cardiac Conduction Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation Negative Regulation Of Myoblast Proliferation Positive Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Cell Migration Involved In Coronary Vasculogenesis Positive Regulation Of Mesoderm Formation Positive Regulation Of Mesoderm Development Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Cell Migration Involved In Vasculogenesis Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Negative Regulation Of Response To Drug Positive Regulation Of Sarcomere Organization Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Activation-induced Cell Death Of T Cells Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Mesoderm Development Activated T Cell Proliferation Regulation Of Membrane Repolarization During Action Potential Positive Regulation Of Cardiac Muscle Contraction Regulation Of Response To Drug Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Cardiac Muscle Cell Differentiation Negative Regulation Of Endothelial Cell Differentiation Positive Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Sarcomere Organization Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Positive Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Interleukin-2-mediated Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Proliferation Regulation Of T Cell Tolerance Induction Positive Regulation Of Cell Fate Commitment Positive Regulation Of Myotube Differentiation Positive Regulation Of Striated Muscle Contraction Positive Regulation Of Cardiocyte Differentiation Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Metabolic Process Nucleic Acid Metabolic Process MRNA Processing RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of RNA Splicing Macromolecule Metabolic Process Nucleoplasm Nucleus Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Post-transcriptional Regulation Of Gene Expression Spliceosomal Complex Regulation Of MRNA Processing Catalytic Step 2 Spliceosome Cytoplasmic Stress Granule Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Negative Regulation Of RNA Catabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process MiRNA Binding RNA Stabilization TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Metabolic Process TRNA Aminoacylation Ligase Activity MRNA Stabilization Negative Regulation Of Macromolecule Metabolic Process Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation Regulation Of MRNA Stability Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process
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