MSRB2 and ZDHHC17

Number of citations of the paper that reports this interaction (PubMedID 24705354)
111

Data Source:
BioGRID (two hybrid)

		MSRB2	ZDHHC17
Description		methionine sulfoxide reductase B2	zDHHC palmitoyltransferase 17
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Golgi Membrane Golgi Apparatus Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Golgi-associated Vesicle Membrane Cytoplasmic Vesicle Presynaptic Membrane Cell Projection Synapse Glutamatergic Synapse Perforant Pathway To Dendrate Granule Cell Synapse Postsynaptic Golgi Apparatus
	Molecular Function	Actin Binding Protein Binding Zinc Ion Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor Peptide-methionine (R)-S-oxide Reductase Activity L-methionine-(R)-S-oxide Reductase Activity Metal Ion Binding	Signaling Receptor Binding Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Identical Protein Binding Protein-cysteine S-stearoyltransferase Activity
	Biological Process	Response To Oxidative Stress Actin Filament Polymerization Protein Repair	Axonogenesis Protein Palmitoylation Lipoprotein Transport Regulation Of Programmed Cell Death Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission
Pathways		Protein repair
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Obesity-related traits ( 23251661)	Mean arterial pressure x educational attainment (some college) interaction (2df) ( 32372009) Metabolite levels ( 23823483) Visceral fat ( 30942860)
Interacting Genes		5 interacting genes: CACNB2 NRP1 RAD21 TRAF2 ZDHHC17	194 interacting genes: ABCG4 ACTR1B ADD1 AHDC1 AIDA AK3 ALKBH3 ANKRD50 ANXA11 APBB1IP ARFGAP3 ASF1A ASIC4 BCAS3 BEX2 BTF3 C1orf216 C20orf141 CBS CCDC120 CCDC7 CCNE2 CDSN CENPBD2P CHMP1A CIB1 CLRN3 CNDP2 CNKSR1 COG3 CSTA CTCFL CTHRC1 DALRD3 DELE1 DIXDC1 DLG4 DLK1 DR1 DTX3 E2F8 EDRF1 EEF1G ERCC6L EVL EXOSC9 EYA3 FAM9A FBH1 FOXD4L6 FTL FUT2 FUT9 GABPB1 GABPB2 GATA1 GOLPH3L GPR135 GRB10 GUSBP3 H2AP H2BC9 H3C10 HBG1 HECTD3 HLA-A HLA-DRB1 HMBS HOXA3 HS1BP3 HTT IFT20 IFT57 INPP5D JMJD7-PLA2G4B KHDC4 KIAA0408 KNSTRN KRAS KRT17 KRT8P12 KRTAP11-1 KRTAP9-2 LCA5L LCMT1P1 LGALS9C LIN28A LMAN2L LNCRI LRRC45 LY6G6C MANF MAP2K4 MAP3K19 MIIP MLH3 MRFAP1 MRFAP1L1 MSANTD3 MSRB2 MYBPHL MYOZ2 NAP1L1 NCBP1 NEBL NFATC2IP NFYC NIFK NPFF ODF2 OFCC1 OTUD7B OTX2 PABIR3 PBRM1 PDE4DIP PDZK1IP1 PHF5A PLEKHB1 PPP1R21 PPTC7 PRMT5 PTMA QRICH1 RAB39B RAD51 RANGRF RAP1B RBM5 RCAN3 RIC8A RNF20 RNF38 RSBN1L RUBCNL SCNM1 SEMA4G SF3A3 SHOX2 SKA3 SLC1A3 SLC25A31 SLC9A9 SLX9 SMARCB1 SNAP25 SOX14 SP2 SPRY3 SPRY4 SREBF2 SRSF4 STK25 STN1 SUMF2 SYT1 TEAD1 THAP7 TIGD1 TMC6 TMCC1 TMEM115 TMEM186 TMTC1 TNFAIP1 TNFSF10 TOX TPGS2 TTC23 TTLL7 TUT7 TXNDC12 TXNDC15 UBAC1 UBE2K USP18 USP32 VN1R10P VSX2 WAC WDR20 YIF1A YTHDF3 ZCCHC17 ZFC3H1 ZFP2 ZFP36 ZFYVE19 ZNF333 ZNF341 ZNF597 ZNF624 ZNF667-AS1 ZSCAN9
Entrez ID		22921	23390
HPRD ID		17606	09697
Ensembl ID		ENSG00000148450	ENSG00000186908
Uniprot IDs		Q9Y3D2	A8KA01 Q8IUH5
PDB IDs			3EU9 5W7I 5W7J
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Glial Cell Apoptotic Process Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels Membrane Depolarization During Atrial Cardiac Muscle Cell Action Potential Intracellular Protein Localization Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Voltage-gated Calcium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Calcium Channel Activity Involved In Cardiac Muscle Cell Action Potential Establishment Of Meiotic Sister Chromatid Cohesion Regulation Of Programmed Cell Death TORC2 Complex Disassembly Regulation Of Extrinsic Apoptotic Signaling Pathway TRAF2-GSTP1 Complex TORC1 Complex Assembly Regulation Of MAPK Cascade CD40 Receptor Binding Otic Placode Development Ventral Trunk Neural Crest Cell Migration Vestibulocochlear Nerve Structural Organization Renal Artery Morphogenesis VEGF-activated Neuropilin Signaling Pathway Basal Dendrite Development Basal Dendrite Arborization Trigeminal Nerve Morphogenesis Angiogenesis Involved In Coronary Vascular Morphogenesis Basal Dendrite Morphogenesis Blood Vessel Endothelial Cell Fate Specification Protein Localization To Early Endosome Facioacoustic Ganglion Development Endothelial Tip Cell Fate Specification Dorsal Root Ganglion Morphogenesis Sensory Neuron Axon Guidance Axonogenesis Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex Trigeminal Ganglion Development Sympathetic Neuron Projection Guidance Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Endothelial Cell Fate Specification Vascular Endothelial Growth Factor Binding Neuropilin Signaling Pathway Receptor Complex Membrane Depolarization During AV Node Cell Action Potential Meiotic Cohesin Complex	Protein Binding
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