CLSTN1 and MCM3AP

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		CLSTN1	MCM3AP
Description		calsyntenin 1	minichromosome maintenance complex component 3 associated protein
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Cell Surface Postsynaptic Density Membrane Cell Projection Neuron Projection Synapse Postsynaptic Membrane Postsynaptic Endosome Glutamatergic Synapse	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Chromosome Cytoplasm Cytosol Nuclear Membrane Protein-containing Complex Nuclear Pore Nuclear Basket Transcription Export Complex 2
	Molecular Function	Amyloid-beta Binding Calcium Ion Binding Protein Binding Kinesin Binding X11-like Protein Binding	Nucleic Acid Binding Chromatin Binding Histone Acetyltransferase Activity Protein Binding Histone H3 Acetyltransferase Activity Transferase Activity Acyltransferase Activity Histone Binding
	Biological Process	Regulation Of Cell Growth Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Positive Regulation Of Synaptic Transmission Positive Regulation Of Synapse Assembly Regulation Of Synapse Maturation Neurotransmitter Receptor Transport To Postsynaptic Membrane Vesicle-mediated Transport In Synapse	Immune System Process MRNA Export From Nucleus Protein Transport Somatic Hypermutation Of Immunoglobulin Genes Poly(A)+ MRNA Export From Nucleus Nucleosome Organization MRNA Transport
Pathways
Drugs
Diseases
GWAS			Monocyte percentage of white cells ( 32888494) Periodontitis ( 30218097) Testicular germ cell tumor ( 23666240 25877299 28604728)
Interacting Genes		14 interacting genes: APBA2 APBB1 BAHCC1 COL17A1 KIF2A KLC1 KLC2 MCM3AP MDM2 PRNP SETDB1 SLK TOPBP1 TRIP12	19 interacting genes: APC CDC25A CDC42 CDC73 CLSTN1 CRMP1 ENY2 EP300 FAM118B MCM3 NUDT5 POLR2G RAC1 SMAD3 SMAD9 SUV39H2 TAF1D TMEM216 TSC22D1
Entrez ID		22883	8888
HPRD ID		10837	04483
Ensembl ID		ENSG00000171603	ENSG00000160294
Uniprot IDs		B4E3Q1 O94985	O60318
PDB IDs			4DHX
Enriched GO Terms of Interacting Partners?		Kinesin Complex Amyloid-beta Binding Heterochromatin Organization Negative Regulation Of Protein Processing Negative Regulation Of Protein Maturation Chromatin Organization Chromatin Binding Cytoskeletal Motor Activity Kinesin Binding Response To Formaldehyde Cellular Response To Vitamin B1 Type 8 Metabotropic Glutamate Receptor Binding Kinesin I Complex Regulation Of Protein Processing Protein Destabilization Regulation Of Protein Maturation	Cell-cell Junction Organization Leading Edge Membrane Wnt Signaling Pathway Nucleus Thioesterase Binding G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Bundle Assembly SMAD Protein Complex Heteromeric SMAD Protein Complex Positive Regulation Of Pseudopodium Assembly Protein Kinase Binding I-SMAD Binding Beta-catenin Binding Positive Regulation Of Cellular Component Biogenesis Regulation Of Stress Fiber Assembly Regulation Of Cell Junction Assembly Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Cell Junction Assembly GTP-dependent Protein Binding Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore Regulation Of Synapse Organization Regulation Of Primary Metabolic Process Positive Regulation Of Cell-substrate Adhesion SMAD Protein Signal Transduction Positive Regulation Of Lamellipodium Assembly Regulation Of Postsynapse Organization Phagocytosis, Engulfment Positive Regulation Of Focal Adhesion Assembly Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Projection Organization Regulation Of Cell Projection Organization Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Lamellipodium Organization Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cellular Component Organization Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cellular Component Organization Nucleoplasm Cell Surface Receptor Signaling Pathway Regulation Of Supramolecular Fiber Organization Cytosol Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Supramolecular Fiber Organization Regulation Of Cell Growth Regulation Of Lamellipodium Assembly
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