TMEM130 and TMEM100

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM130	TMEM100
Description		transmembrane protein 130	transmembrane protein 100
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Plasma Membrane Membrane	Cytoplasm Endoplasmic Reticulum Plasma Membrane Membrane Perikaryon Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Angiogenesis Vasculogenesis In Utero Embryonic Development Endocardial Cushion Development Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Notch Signaling Pathway Cell Differentiation BMP Signaling Pathway Positive Regulation Of Endothelial Cell Differentiation Regulation Of Calcium-mediated Signaling Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Sensory Perception Of Pain Arterial Endothelial Cell Differentiation Cellular Response To BMP Stimulus Positive Regulation Of Vasculogenesis
Pathways
Drugs
Diseases
GWAS		Decreased low contrast letter acuity in multiple sclerosis ( 31289819)	Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 27400856) Height ( 22021425) Pulse pressure ( 30578418) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		10 interacting genes: GRM2 NKG7 OLFM4 PIGF SLC2A5 SLC35B4 SLC61A1 TMEM100 TSPAN2 YIPF6	33 interacting genes: AQP6 CCDC57 CD33 CLDN7 COMT CREB3 EBP ERGIC3 F11R FAM209A FNDC9 GJA8 GPR152 HSD17B13 IFNGR1 JAGN1 LHFPL5 MEOX2 NUP93 REEP1 RETREG3 RMDN3 RNF19B SLC30A4 SLC35A5 STING1 STX1A TMEM130 TMEM167B TMEM52B TMEM79 TMEM80 VSIR
Entrez ID		222865	55273
HPRD ID		13226	07719
Ensembl ID		ENSG00000166448	ENSG00000166292
Uniprot IDs		Q8N3G9	Q9NV29
PDB IDs
Enriched GO Terms of Interacting Partners?		Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Fructose Import Across Plasma Membrane UDP-xylose Transmembrane Transport UDP-xylose Transmembrane Transporter Activity Molybdate Ion Transmembrane Transporter Activity Molybdate Ion Transport Organic Anion Transport Group II Metabotropic Glutamate Receptor Activity Membrane Ethanolaminephosphotransferase Activity Microglia Development UDP-N-acetylglucosamine Transmembrane Transporter Activity UDP-N-acetylglucosamine Transmembrane Transport	Membrane
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