TSPO2 and SLC41A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSPO2	SLC41A3
Description		translocator protein 2	solute carrier family 41 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Organelle Membrane	Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Membrane
	Molecular Function	Protein Binding Cholesterol Binding 5-aminolevulinic Acid Transmembrane Transporter Activity	Protein Binding Monoatomic Cation Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Magnesium:sodium Antiporter Activity
	Biological Process	Intracellular Cholesterol Transport Lipid Droplet Organization Enucleate Erythrocyte Differentiation Import Across Plasma Membrane 5-aminolevulinic Acid Import Across Plasma Membrane	Monoatomic Ion Transport Monoatomic Cation Transport Sodium Ion Transmembrane Transport Mitochondrial Magnesium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Gastric cancer ( 26129866) Non-cardia gastric cancer ( 26129866)	Bell's palsy ( 33602968)
Interacting Genes		63 interacting genes: AHNAK2 AQP6 ARL13B ASGR2 ASZ1 BIK CD53 CD69 CD79A CERS4 CLDN4 CNR2 COL4A5 CPLX4 CREB3L1 DKK4 EBP EFNA5 EMP1 ERGIC3 ERP29 FCER1G FCGR1A FFAR2 FKBP7 FNDC9 FXYD3 GGT7 GJB5 GPR152 GPR42 GPX8 IGFBP5 KCNJ6 KLRC1 LRRC59 MAL MARCHF2 MFF MFSD6 MS4A1 PDZK1IP1 PLEKHO1 PSCA RELL2 RETREG3 RPRM RSPH9 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC34A2 SLC35H1 SLC41A3 SLC7A1 SPAG4 STOM SYT2 TMEM140 TMEM54 TMEM80 VSIR	17 interacting genes: APP ARLN CCL3L3 CCR2 CREB3 GPR37 IGFBP5 MAPK6 NHERF4 NPSR1 PLP1 REL SMCO4 SMO SUFU TMBIM6 TSPO2
Entrez ID		222642	54946
HPRD ID		16569	11580
Ensembl ID		ENSG00000112212	ENSG00000114544
Uniprot IDs		Q5TGU0	Q96GZ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I External Side Of Plasma Membrane Positive Regulation Of Type III Hypersensitivity Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Type IIa Hypersensitivity Positive Regulation Of Acute Inflammatory Response Bile Acid:sodium Symporter Activity Transmembrane Transport Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Hypersensitivity Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Antigen Processing And Presentation Of Exogenous Peptide Antigen Sodium Ion Transport Regulation Of Acute Inflammatory Response Antigen Processing And Presentation Of Exogenous Antigen Immune Response-regulating Signaling Pathway Serotonin Transport	Positive Regulation Of Monocyte Chemotaxis Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Monocyte Chemotaxis Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Signal Transduction Positive Regulation Of Locomotion Locomotion Regulation Of Signal Transduction Spinal Cord Dorsal/ventral Patterning Regulation Of Calcium Ion Transport G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Mononuclear Cell Migration Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Leukocyte Chemotaxis Astrocyte Activation Neuropeptide Receptor Activity Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Migration Chemotaxis Regulation Of Metal Ion Transport Regulation Of Cell Motility Regulation Of Intracellular Signal Transduction Regulation Of Calcium Ion Transmembrane Transport Regulation Of Locomotion Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Endoplasmic Reticulum Positive Regulation Of Leukocyte Migration G Protein-coupled Receptor Activity Hair Follicle Morphogenesis Regulation Of Protein Localization To Nucleus Regulation Of Transport Amyloid-beta Complex Growth Cone Lamellipodium Intracellular Signal Transduction Regulation Of Monoatomic Ion Transport Regulation Of Response To Calcium Ion Positive Regulation Of Cell Communication Dendrite Amylin Binding Positive Regulation Of Signaling Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of T Cell Migration Positive Regulation Of Signal Transduction Dendrite Development
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