CCDC89 and LRRC45

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC89	LRRC45
Description		coiled-coil domain containing 89	leucine rich repeat containing 45
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Centrosome Cytosol Cytoskeleton Plasma Membrane Ciliary Basal Body
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Refractive error ( 32231278)	Neuroblastoma (pediatric) ( 32599975) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: BMPR2 FAM50B LRRC45 PIK3R3 TSFM	13 interacting genes: ALAS1 CCDC89 CENPX KXD1 MCC MID2 MYADML2 RBFOX3 SSX2 SSX2B SSX7 THAP11 ZDHHC17
Entrez ID		220388	201255
HPRD ID		08234	14476
Ensembl ID		ENSG00000179071	ENSG00000169683
Uniprot IDs		Q8N998	Q96CN5
PDB IDs		8WQA 8WQB 8WQD 8WQH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Axon Extension Involved In Axon Guidance Negative Regulation Of Chondrocyte Proliferation Regulation Of Lung Blood Pressure Aortic Valve Development Lymphatic Endothelial Cell Differentiation BMP Receptor Activity Pulmonary Valve Development Tricuspid Valve Morphogenesis Venous Blood Vessel Development Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Activin Receptor Activity, Type II Endochondral Bone Morphogenesis Transforming Growth Factor Beta Receptor Activity Semi-lunar Valve Development Mitral Valve Morphogenesis 1-phosphatidylinositol-3-kinase Regulator Activity Phosphatidylinositol 3-kinase Complex Mitochondrial Translational Elongation Maternal Placenta Development Lung Vasculature Development Pharyngeal Arch Artery Morphogenesis Endothelial Cell Apoptotic Process 1-phosphatidylinositol-3-kinase Activity Phosphatidylinositol 3-kinase Complex, Class IA Transmembrane Receptor Protein Serine/threonine Kinase Activity Negative Regulation Of Vasoconstriction Endocardial Cushion Development Intracellular Organelle Lumen Lymphangiogenesis Retina Vasculature Development In Camera-type Eye Regulation Of Axon Extension Involved In Axon Guidance Atrial Septum Morphogenesis
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