PATL1 and SELENOH

		PATL1	SELENOH
Description		PAT1 homolog 1, processing body mRNA decay factor	selenoprotein H
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol PML Body Nuclear Speck CCR4-NOT Complex Cytoplasmic Ribonucleoprotein Granule	Golgi Apparatus
	Molecular Function	RNA Binding Protein Binding Poly(U) RNA Binding Poly(G) Binding	RNA Binding
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA P-body Assembly
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS
Interacting Genes		26 interacting genes: APP CLK2 DMRTB1 FHL3 GOLGA2 KRT31 KRTAP6-2 LSM2 LSM6 MIR1-2 MIR138-2 MIR15B MIR19B1 MIR19B2 MIR20B MIR21 MIR25 MIR29B2 NFKBID PSMA3 RBPMS SELENOH SNCA TSC1 WWOX ZMYND12	2 interacting genes: OOSP2 PATL1
Entrez ID		219988	280636
HPRD ID		08214	07447
Ensembl ID		ENSG00000166889	ENSG00000211450
Uniprot IDs		Q86TB9	Q8IZQ5
PDB IDs		2XEQ 2XER 2XES
Enriched GO Terms of Interacting Partners?		RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Extracellular Vesicle Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Lsm2-8 Complex MiRNA-mediated Gene Silencing By Inhibition Of Translation U6 SnRNP Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of T-helper 17 Cell Differentiation Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Negative Regulation Of Endothelial Cell Migration Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Vascular Endothelial Growth Factor Production Adult Locomotory Behavior Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Protein Tetramerization Regulation Of Inflammatory Response Positive Regulation Of T-helper 17 Type Immune Response Regulation Of Neurotransmitter Uptake P-body Negative Regulation Of Smooth Muscle Cell Differentiation Regulation Of Non-canonical NF-kappaB Signal Transduction Cellular Response To Copper Ion Negative Regulation Of Autophagy Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of T-helper Cell Differentiation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport	Poly(G) Binding Poly(U) RNA Binding Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Decapping MRNA Methylguanosine-cap Decapping P-body Assembly CCR4-NOT Complex Oocyte Maturation
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