EVI2B and DESI1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EVI2B	DESI1
Description		ecotropic viral integration site 2B	desumoylating isopeptidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Peptidase Activity Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity DeSUMOylase Activity Identical Protein Binding Long-chain Fatty Acyl-CoA Hydrolase Activity Importin-alpha Family Protein Binding
	Biological Process	Positive Regulation Of Granulocyte Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Neutrophil Differentiation Regulation Of Cell Cycle Myeloid Cell Development Regulation Of Stem Cell Division	Proteolysis Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Macromolecule Depalmitoylation
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Oily fish consumption ( 32066663) Pork consumption ( 32066663)	General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		32 interacting genes: APOD AQP1 AQP3 BTN2A2 CDIPT CLN6 CNIH1 CRYBA1 DESI1 DRAM1 FAM3C FUNDC2 GALNT15 GIMAP5 MYADML2 NINJ2 NSG1 PGRMC1 RTP2 SCAMP4 SLC2A5 SLC30A2 SLC38A7 SLC39A9 TMEM107 TMEM222 TMEM60 TMEM86B TRAF3IP3 TRAM1L1 UBIAD1 VAMP4	35 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CENPM CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RBX1 RNF4 RPS27A SHISA4 SHISA5 SLC25A17 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLNL UHRF2 XPO1 ZBTB46
Entrez ID		2124	27351
HPRD ID		08867	18590
Ensembl ID		ENSG00000185862	ENSG00000100418
Uniprot IDs		P34910 Q9BRW1	Q6ICB0
PDB IDs			3EBQ
Enriched GO Terms of Interacting Partners?		Membrane Polyol Transmembrane Transport Renal Water Transport Renal Water Absorption Glycerol Transmembrane Transport Carbohydrate Transport Carbohydrate Transmembrane Transport Lysosome Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Water Channel Activity Endosome To Plasma Membrane Protein Transport Neurotransmitter Receptor Transport Protein Binding Renal Water Homeostasis Lysosomal Membrane Establishment Of Protein Localization To Membrane Golgi Apparatus Endoplasmic Reticulum Negative Regulation Of Lipoprotein Lipid Oxidation Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Multicellular Organismal-level Water Homeostasis One-carbon Compound Transport Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Water Transport Fructose Import Across Plasma Membrane Zinc Ion Import Into Zymogen Granule Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Intracellular Zinc Ion Homeostasis Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Protein Localization To Postsynapse Protein Localization To Postsynaptic Membrane Trans-Golgi Network Membrane CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Multivesicular Body Membrane Postsynaptic Neurotransmitter Receptor Cycle Neurotransmitter Receptor Cycle Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity D-lysine 5,6-aminomutase Activity	Protein Tag Activity TRNA Threonylcarbamoyladenosine Metabolic Process Modification-dependent Protein Catabolic Process Endocytic Vesicle Membrane Ubiquitin Protein Ligase Binding Mitochondrial Outer Membrane Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Regulation Of Granulocyte Differentiation Protein Modification By Small Protein Conjugation Vesicle
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