EPHB6 and ASB12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EPHB6	ASB12
Description		EPH receptor B6	ankyrin repeat and SOCS box containing 12
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Membrane Dendrite	Ubiquitin Ligase Complex Cytosol
	Molecular Function	Nucleotide Binding Protein Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Protein Binding ATP Binding Signaling Receptor Activity	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Ephrin Receptor Signaling Pathway	Protein Ubiquitination
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Fostamatinib
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576) Cancer ( 29299148)
Interacting Genes		28 interacting genes: AFDN ASB12 CBL CRK CRKL DDIT4L DUSP18 DUSP19 EFNB2 EPHB1 ERBB2 GRB2 HDHD2 INCA1 MSX2 MTARC1 NIF3L1 NOTCH2NLA POU6F2 PRMT5 REL SAT1 STYX TCF4 TEKT5 TRIB3 TRIM39 VPS26C	8 interacting genes: EPHB6 HGS HSD3B7 KLHL38 LENG1 LZTR1 TLX3 TSEN15
Entrez ID		2051	142689
HPRD ID		04133	06451
Ensembl ID		ENSG00000106123	ENSG00000198881
Uniprot IDs		A0A0G2JNH7 F8WCM8 O15197	Q8WXK4
PDB IDs		7K7J
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Binding Regulation Of MAPK Cascade Phosphotyrosine Residue Binding Regulation Of Signal Transduction Receptor Tyrosine Kinase Binding Helper T Cell Diapedesis Cerebellar Neuron Development Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Enzyme-linked Receptor Protein Signaling Pathway Diapedesis Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein Kinase Inhibitor Activity Cellular Response To Growth Factor Stimulus Ephrin Receptor Signaling Pathway Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Cell Adhesion Postsynaptic Specialization Assembly Response To Growth Factor Positive Regulation Of Receptor Clustering Reelin-mediated Signaling Pathway Positive Regulation Of Small GTPase Mediated Signal Transduction Neuromuscular Junction Cerebral Cortex Development Regulation Of Receptor Clustering Positive Regulation Of Rac Protein Signal Transduction Schwann Cell Development Protein Tyrosine/serine/threonine Phosphatase Activity Establishment Of Cell Polarity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Postsynaptic Specialization Organization SH3 Domain Binding Neuron Projection Development Regulation Of Protein Serine/threonine Kinase Activity Cytoplasm Signal Transduction Protein Binding Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Cell Adhesion Regulation Of Rac Protein Signal Transduction T Cell Migration Identical Protein Binding Guanyl-nucleotide Exchange Factor Adaptor Activity Spermidine Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?