PRSS55 and C8orf74

		PRSS55	C8orf74
Description		serine protease 55	chromosome 8 open reading frame 74
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cytosol Plasma Membrane Membrane Side Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity	Protein Binding
	Biological Process	Proteolysis Binding Of Sperm To Zona Pellucida Flagellated Sperm Motility
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Brain morphology (MOSTest) ( 32665545) General factor of neuroticism ( 30867560) Obesity-related traits ( 23251661) Refractive error ( 32231278) Smoking status (ever vs never smokers) ( 30643258) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Alanine aminotransferase levels ( 33547301) Autism spectrum disorder ( 30804558) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Fish- and plant-related diet ( 32066663) Processed meat consumption ( 32066663) Suicide ( 26079190)
Interacting Genes		1 interacting genes: C8orf74	14 interacting genes: DEFB105A DEFB106A DEFB107A DEFB130A KDM1A PRMT6 PRSS55 SUV39H1 SUV39H2 TDH TRIM54 TRIM55 TRIM63 ZNF655
Entrez ID		203074	203076
HPRD ID		07162	19096
Ensembl ID		ENSG00000184647	ENSG00000171060
Uniprot IDs		Q6UWB4	A0AAG2TK55 Q6P047
PDB IDs
Enriched GO Terms of Interacting Partners?			Histone H3 Methyltransferase Activity Defense Response To Other Organism Defense Response To Symbiont Histone Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity Innate Immune Response Response To Other Organism Immune Response Response To Stress Histone H3K9 Methyltransferase Activity Response To External Biotic Stimulus Defense Response Epigenetic Programming In The Zygotic Pronuclei Defense Response To Bacterium Response To Bacterium Methyltransferase Activity Immune System Process Epigenetic Programming Of Gene Expression Methylation Histone H2AR3 Methyltransferase Activity Epigenetic Regulation Of Gene Expression Chromatin Remodeling Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Histone H3R2 Methyltransferase Activity Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation ENoSc Complex Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Histone Arginine N-methyltransferase Activity Microtubule Defense Response To Gram-negative Bacterium Zinc Ion Binding Ubiquitin Protein Ligase Activity Protein Demethylase Activity CCR2 Chemokine Receptor Binding RDNA Heterochromatin Chromatin Organization MRF Binding Protein-arginine Omega-N Monomethyltransferase Activity Histone H4R3 Methyltransferase Activity Skeletal Muscle Atrophy Defense Response To Gram-positive Bacterium Regulation Of Signal Transduction By P53 Class Mediator
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