EMP1 and CD37

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EMP1	CD37
Description		epithelial membrane protein 1	CD37 molecule
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Immunological Synapse Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Apoptotic Process Epidermis Development Bleb Assembly	Positive Regulation Of Immunoglobulin Production Regulation Of Humoral Immune Response Negative Regulation Of Myeloid Dendritic Cell Activation T Cell Proliferation Negative Regulation Of T Cell Proliferation Defense Response To Protozoan Regulation Of Defense Response To Virus
Pathways
Drugs			Otlertuzumab
Diseases
GWAS		Coronary artery calcification ( 23870195) Degraded stimulus continuous performance test score ( 31596458) Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136) Heel bone mineral density ( 28869591 30598549) Household income (MTAG) ( 31844048) Refractive error ( 32231278) Serum albumin levels ( 29403010)
Interacting Genes		63 interacting genes: ANK1 ANKS6 APOL2 AQP6 ARL13B ARL6IP1 ASGR2 ATP6V0B ATP6V0E1 BTN2A2 C1QBP CATSPERH CCR5 CD37 CD3G CD40 CD53 CD79A CEP70 CLDN9 CORIN CXCR2 EBP EDA EHHADH ERGIC3 FFAR2 GIMAP5 GPR42 GPRC5D HTR2C ISLR2 JPH1 KLRC1 LAPTM4B LEPROTL1 LHFPL5 LPAR6 LRRC3B LSMEM2 MAL MALL MS4A7 OPRM1 PLEKHB2 PMP22 RABAC1 RPRM SERTM1 SMIM3 SPACA1 STOM SYNE4 TBXA2R TEX264 TLCD4 TMEM114 TMEM160 TMEM218 TMEM239 TMEM31 TMEM9 TSPO2	6 interacting genes: AGTR1 CD53 EMP1 GJB1 LHFPL5 LRRC3B
Entrez ID		2012	951
HPRD ID		11892	01053
Ensembl ID		ENSG00000134531	ENSG00000104894
Uniprot IDs		P54849	P11049
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding G Protein-coupled Receptor Activity External Side Of Plasma Membrane Immune Response-regulating Cell Surface Receptor Signaling Pathway Multivesicular Body Membrane	Angiotensin Type I Receptor Activity Plasma Membrane Phospholipase C-activating Angiotensin-activated Signaling Pathway Bradykinin Receptor Binding Renin-angiotensin Regulation Of Aldosterone Production Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Regulation Of Renal Sodium Excretion Membrane Bleb Assembly Gap Junction Assembly Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Stereocilium Bundle
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