ELAVL2 and GLIPR2

		ELAVL2	GLIPR2
Description		ELAV like RNA binding protein 2	GLI pathogenesis related 2
Image		No pdb structure
GO Annotations	Cellular Component	Ribonucleoprotein Complex	Golgi Membrane Extracellular Region Extracellular Space Golgi Apparatus Membrane Extracellular Exosome
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding	Protein Homodimerization Activity
	Biological Process	Regulation Of DNA-templated Transcription	Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial To Mesenchymal Transition Sexual Reproduction Positive Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs			L-cysteic acid
Diseases
GWAS		Anxiety ( 33859377) Asthma ( 34103634 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Attending social / leisure activities ( 34054130) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Chronic obstructive pulmonary disease ( 30804561) Feeling guilty ( 29500382) Femur bone mineral density x serum urate levels interaction ( 34046847) Fulminant type 1 diabetes ( 30552108) General cognitive ability ( 29844566) Glomerular filtration rate change in heart transplantation ( 30160337) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Lung function (FEV1/FVC) ( 30061609) Neurociticism ( 29500382) Neuroticism ( 27067015 29255261 27089181) Physiological traits ( 31902109) Plasma t-tau levels ( 28100725) Remission after SSRI treatment in MDD or neuroticism ( 29559929) Schizophrenia ( 33169155) Sociability score ( 34054130)	Bipolar disorder (inflammation and infection response interaction) ( 25781172)
Interacting Genes		10 interacting genes: CDKN2B ELAVL3 ELAVL4 GLIPR2 HNRNPAB HOXC9 IL11RA NR2E3 RBFOX2 SECISBP2	5 interacting genes: CDKN2A ELAVL2 FBXO7 KRTAP10-3 PNMA5
Entrez ID		1993	152007
HPRD ID		03396	06187
Ensembl ID		ENSG00000107105	ENSG00000122694
Uniprot IDs		A0A0A0MRX1 Q12926	A0A087WUM5 A0A088AWP7 Q5VZR0 Q9H4G4
PDB IDs			1SMB 4AIW 5VHG
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MRNA Catabolic Process Regulation Of MRNA Metabolic Process Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Metabolic Process Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Ribonucleoprotein Complex MRNA 3'-UTR Binding Developmental Process MRNA 3'-UTR AU-rich Region Binding Nucleic Acid Binding Cellular Developmental Process MRNA Binding Negative Regulation Of RNA Metabolic Process RNA Metabolic Process MRNA Stabilization Cell Differentiation RNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Stabilization Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Pre-mRNA Intronic Pyrimidine-rich Binding Negative Regulation Of Catabolic Process Nuclear Receptor-mediated Signaling Pathway Cellular Response To Cell-matrix Adhesion MRNA Editing Complex Interleukin-11 Receptor Activity Interleukin-11 Binding Selenocysteine Insertion Sequence Binding Chromosomal 5-methylcytosine DNA Demethylation Pathway Hormone-mediated Signaling Pathway Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Nucleic Acid Metabolic Process Regulation Of Intracellular MRNA Localization Neuronal Ribonucleoprotein Granule Positive Regulation Of Gene Expression Interleukin-11-mediated Signaling Pathway MRNA Metabolic Process Neuron Development Selenocysteine Incorporation Regulation Of MRNA Stability Regulation Of RNA Metabolic Process Regulation Of RNA Stability Megakaryocyte Differentiation Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Intracellular Receptor Signaling Pathway	Negative Regulation Of Lymphocyte Differentiation Autophagy Of Mitochondrion Ligase Inhibitor Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Negative Regulation Of Hemopoiesis Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Lymphocyte Activation Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Leukocyte Activation Senescence-associated Heterochromatin Focus Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Immature T Cell Proliferation In Thymus Apoptotic Process Involved In Mammary Gland Involution Lewy Body Core Regulation Of Lymphocyte Differentiation Negative Regulation Of Cell Activation Negative Regulation Of Immature T Cell Proliferation Mitochondrial Depolarization Oncogene-induced Cell Senescence Positive Regulation Of Apoptotic Process Involved In Morphogenesis Negative Regulation Of Ubiquitin Protein Ligase Activity Positive Regulation Of Apoptotic Process Involved In Development Somatic Stem Cell Division Protein Localization To Nucleolus Negative Regulation Of Cyclin-dependent Protein Kinase Activity MDM2/MDM4 Family Protein Binding Regulation Of Mitotic Cell Cycle Phase Transition Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Polyubiquitination Ubiquitin Ligase Inhibitor Activity Autophagy Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of Cell Development Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Sumoylation Negative Regulation Of Cell Cycle Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Stability Regulation Of Mammary Gland Epithelial Cell Proliferation Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
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