LINC00311 and DNAAF1

		LINC00311	DNAAF1
Description		long intergenic non-protein coding RNA 311	dynein axonemal assembly factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Spindle Pole Extracellular Region Cytoplasm Cytoskeleton Cilium Axoneme Cell Projection
	Molecular Function		Dynein Complex Binding
	Biological Process		Heart Looping Cilium Movement Regulation Of Cilium Beat Frequency Lung Development Axoneme Assembly Determination Of Pancreatic Left/right Asymmetry Outer Dynein Arm Assembly Inner Dynein Arm Assembly Motile Cilium Assembly Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Left/right Pattern Formation Axonemal Dynein Complex Assembly Determination Of Digestive Tract Left/right Asymmetry Determination Of Liver Left/right Asymmetry
Pathways
Drugs
Diseases			Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
GWAS		Systolic blood pressure ( 30224653) Triglyceride levels x loop diuretics use interaction ( 31806883)	Post bronchodilator FEV1/FVC ratio ( 26634245) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		2 interacting genes: CD2 DNAAF1	2 interacting genes: KCNG4 LINC00311
Entrez ID		197196	123872
HPRD ID		14484	14023
Ensembl ID		ENSG00000179219	ENSG00000154099
Uniprot IDs			A0A140VJN4 Q8NEP3
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Raft Distribution Membrane Raft Polarization Membrane Raft Localization Positive Regulation Of Myeloid Dendritic Cell Activation Determination Of Pancreatic Left/right Asymmetry Determination Of Liver Left/right Asymmetry Determination Of Digestive Tract Left/right Asymmetry Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Left/right Pattern Formation Inner Dynein Arm Assembly Regulation Of Cilium Beat Frequency Outer Dynein Arm Assembly Dynein Complex Binding Membrane Raft Organization Heterotypic Cell-cell Adhesion Regulation Of Cilium Movement Axonemal Dynein Complex Assembly Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity Motile Cilium Assembly Epithelial Cilium Movement Involved In Extracellular Fluid Movement Natural Killer Cell Activation Axoneme Assembly Extracellular Transport Regulation Of Microtubule-based Movement Receptor Tyrosine Kinase Binding Positive Regulation Of Interleukin-8 Production Heart Looping Embryonic Heart Tube Morphogenesis Positive Regulation Of Type II Interferon Production Leukocyte Mediated Cytotoxicity Regulation Of Interleukin-8 Production Determination Of Bilateral Symmetry Microtubule Bundle Formation Determination Of Left/right Symmetry
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