RILPL2 and HEXD

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RILPL2	HEXD
Description		Rab interacting lysosomal protein like 2	hexosaminidase D
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoskeleton Cilium Membrane Ciliary Basal Body Cell Projection	Nucleus Cytoplasm Extracellular Vesicle
	Molecular Function	Protein Binding Small GTPase Binding Identical Protein Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding	Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Beta-N-acetylhexosaminidase Activity Hexosaminidase Activity Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds
	Biological Process	Epithelial Cell Morphogenesis Protein Transport Cilium Assembly Protein Transport From Ciliary Membrane To Plasma Membrane	Carbohydrate Metabolic Process
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Alanine aminotransferase levels ( 33547301) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Educational attainment ( 25201988) Height ( 28552196) High density lipoprotein cholesterol levels ( 29403010) Hip circumference adjusted for BMI ( 34021172) Lymphocyte count ( 27863252) Schizophrenia ( 25056061 29483656 23974872) Tourette syndrome ( 30818990) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: DNAH10 HEXD TUBB3	9 interacting genes: ADPRS C7orf25 EEF1D GDPD2 GLRX3 PRKN PSD RILPL2 TUBB3
Entrez ID		196383	284004
HPRD ID		10084	08677
Ensembl ID		ENSG00000150977	ENSG00000169660
Uniprot IDs		Q969X0	Q8WVB3
PDB IDs		6RIR 6SQ2 7LWB
Enriched GO Terms of Interacting Partners?		Netrin Receptor Binding Dorsal Root Ganglion Development Beta-N-acetylhexosaminidase Activity Hexosaminidase Activity Microtubule Netrin-activated Signaling Pathway Ganglion Development Minus-end-directed Microtubule Motor Activity Axonemal Dynein Complex Peptide Binding Microtubule-based Process 9+2 Motile Cilium Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Dynein Complex Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Microtubule Motor Activity	Heat Shock Protein Binding Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex Regulation Of Necroptotic Process Positive Regulation Of Retrograde Transport, Endosome To Golgi Negative Regulation Of Glucokinase Activity Regulation Protein Catabolic Process At Presynapse Regulation Of Programmed Necrotic Cell Death Negative Regulation Of Intralumenal Vesicle Formation Mitochondrion To Lysosome Vesicle-mediated Transport Mitochondrion-derived Vesicle F-box Domain Binding Positive Regulation Of Protein Linear Polyubiquitination Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Hydrogen Sulfide Negative Regulation Of Spontaneous Neurotransmitter Secretion Response To Curcumin Netrin Receptor Binding Glycerophosphoinositol Inositolphosphodiesterase Activity Poly(ADP-ribose) Glycohydrolase Activity ADP-ribosylserine Hydrolase Activity Cellular Response To Superoxide Peptidyl-serine ADP-deribosylation Protein Transport From Ciliary Membrane To Plasma Membrane Eukaryotic Translation Elongation Factor 1 Complex Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Fusion Cellular Response To L-glutamine Response To Hydrogen Sulfide Negative Regulation Of Exosomal Secretion Glycerophosphodiester Phosphodiesterase Activity O-acetyl-ADP-ribose Deacetylase Activity Cytoplasmic Translational Elongation Lewy Body Regulation Of Spontaneous Synaptic Transmission Type 2 Mitophagy Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Mitochondrial Fission Regulation Of Endosome Organization Positive Regulation Of Mitochondrial Membrane Potential Aggresome Assembly Positive Regulation Of Neurotransmitter Uptake Cell Projection Regulation Of Synaptic Vesicle Transport Dorsal Root Ganglion Development Response To Superoxide Protein De-ADP-ribosylation Free Ubiquitin Chain Polymerization Cellular Response To Dopamine Negative Regulation Of Mitochondrial Fusion Negative Regulation Of Neurotransmitter Secretion
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