DPT and PITRM1

		DPT	PITRM1
Description		dermatopontin	pitrilysin metallopeptidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix	Mitochondrion Mitochondrial Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding	Metalloendopeptidase Activity Protein Binding Enzyme Activator Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Population Proliferation Collagen Fibril Organization	Proteolysis Protein Targeting To Mitochondrion Protein Processing
Pathways			Mitochondrial protein import
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Diisocyanate-induced asthma ( 25918132) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Morbidity-free survival ( 17903295) PR interval ( 32439900) Rosacea symptom severity ( 29771307)	Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Metabolite levels ( 23823483) Scalp hair shape ( 26926045)
Interacting Genes		6 interacting genes: BAG6 CD44 DCN LOX PITRM1 TGFB1	9 interacting genes: BID DPT IDI1 LARP4B MFN2 PNLIPRP1 S100A7 SOCS6 WDR77
Entrez ID		1805	10531
HPRD ID		00510	07142
Ensembl ID		ENSG00000143196	ENSG00000107959
Uniprot IDs		Q07507	A0A0A0MRX9 A0A7I2V397 Q5JRX3
PDB IDs			4L3T 4NGE 4RPU 6XOS 6XOT 6XOU 6XOV 6XOW
Enriched GO Terms of Interacting Partners?		Glycosaminoglycan Catabolic Process Hyaluronan Catabolic Process Hyaluronan Metabolic Process Muscle Cell Cellular Homeostasis Extracellular Matrix Assembly T Cell Activation Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Striated Muscle Tissue Development Regulation Of Muscle Organ Development Glycosaminoglycan Metabolic Process Extracellular Region Collagen Binding Microvillus Regulation Of Developmental Process Extracellular Matrix Negative Regulation Of Endothelial Cell Migration Descending Aorta Development Ascending Aorta Development Connective Tissue Development Branch Elongation Involved In Mammary Gland Duct Branching Positive Regulation Of Microglia Differentiation Cellular Response To Acetaldehyde Lymphocyte Activation Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Leukocyte Activation Positive Regulation Of Monocyte Aggregation Anatomical Structure Morphogenesis Macrophage Migration Inhibitory Factor Receptor Complex Animal Organ Development Golgi Lumen Regulation Of Multicellular Organismal Development Lung Development Positive Regulation Of Primary MiRNA Processing Embryonic Liver Development Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Cell Activation Monocyte Aggregation Peptidyl-lysine Oxidation Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Frontal Suture Morphogenesis BAT3 Complex Negative Regulation Of Hyaluronan Biosynthetic Process Positive Regulation Of Exit From Mitosis Negative Regulation Of Skeletal Muscle Tissue Development Type III Transforming Growth Factor Beta Receptor Binding Langerhans Cell Differentiation Maintenance Of Unfolded Protein Carbohydrate Derivative Catabolic Process Positive Regulation Of ERK1 And ERK2 Cascade	Protein Targeting To Mitochondrion
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