SEPTIN1 and AMOT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SEPTIN1	AMOT
Description		septin 1	angiomotin
Image
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Meiotic Spindle	Stress Fiber Ruffle Cytoplasm Cytosol Actin Filament Plasma Membrane Bicellular Tight Junction COP9 Signalosome External Side Of Plasma Membrane Cell Surface Postsynaptic Density Membrane Lamellipodium Endocytic Vesicle Cytoplasmic Vesicle Anchoring Junction Glutamatergic Synapse
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity	Protein Binding Signaling Receptor Activity Angiostatin Binding
	Biological Process	Spindle Assembly Involved In Female Meiosis Intracellular Protein Localization Regulation Of Exocytosis Cell Division Meiotic Metaphase Chromosome Alignment Cytoskeleton-dependent Cytokinesis	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Vasculogenesis In Utero Embryonic Development Gastrulation With Mouth Forming Second Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Chemotaxis Cell-cell Junction Assembly Intracellular Protein Localization Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Migration Hippo Signaling Positive Regulation Of Embryonic Development Cell Migration Involved In Gastrulation Negative Regulation Of Vascular Permeability Blood Vessel Endothelial Cell Migration Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Cell Size Blood Vessel Morphogenesis Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Stress Fiber Assembly Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Pathways
Drugs
Diseases
GWAS
Interacting Genes		24 interacting genes: AMOT APP AURKB DDIT4L DNAJB13 GORASP2 GPSM1 HSF2BP LNX1 MID2 MRPL12 NIF3L1 PICK1 PIH1D1 SDCBP SEPTIN11 SEPTIN3 SEPTIN5 SEPTIN6 SEPTIN9 TEX11 TOLLIP UBC UBE2I	58 interacting genes: ACTA1 AMOTL2 AP1M1 APP AQP1 AXIN2 C1orf216 CAPN3 DISC1 FHL2 HOXA1 HPCAL1 KIAA1328 KRT14 KRT15 KRT16 KRT19 KRT24 KRT27 KRT31 KRT34 KRT36 KRT75 LCE1D LMNB2 LMO4 LZTS1 MAGEA4 MAGI1 MAPK3 MED4 MEOX2 MIS18A MYBPC1 MYBPC2 MYOM3 NEDD4 NEDD4L NTAQ1 NUFIP2 PBLD PIK3C2A PIN1 PLG PRKAA2 PTEN PTPA RBM48 SEPTIN1 SLIRP SMC1A SNAPC5 SOCS6 THRA TTN UBC UNC119 YAP1
Entrez ID		1731	154796
HPRD ID		15324	02327
Ensembl ID		ENSG00000180096	ENSG00000126016
Uniprot IDs		J3KNL2 Q8WYJ6	Q4VCS5
PDB IDs		6WBE	6JJX 7LP2 7LP3 7LP5 7NMA 7NMW 7NMX 7NN2 7NND 7NNE 7NP2 7NPB 7NPG 7OQG 7OQJ 7OQS 7OQU 7OQW
Enriched GO Terms of Interacting Partners?		Septin Ring Septin Complex Cell Division Site Cytoskeleton-dependent Cytokinesis Molecular Adaptor Activity Microtubule Cytoskeleton Cell Division Cytoplasm GTPase Activity Intracellular Protein Localization Cytoskeleton GTP Binding Regulation Of Receptor Internalization Stress Fiber Synaptonemal Complex Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization Synaptic Vesicle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Frizzled Binding Interleukin-5 Receptor Complex SUMO Conjugating Enzyme Activity Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Phosphoprotein Binding Septin Collar Meiotic Gene Conversion	Cytoskeleton Organization Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Organelle Organization Anatomical Structure Morphogenesis Sarcomere Organization Structural Constituent Of Cytoskeleton Epithelial Cell Differentiation Tissue Morphogenesis Morphogenesis Of An Epithelium Structural Constituent Of Muscle Developmental Process Cytosol M Band Extracellular Exosome Actomyosin Structure Organization Tissue Development Cellular Developmental Process Epidermis Development Protein Binding Actin Cytoskeleton Organization Phosphothreonine Residue Binding Cornified Envelope Cell Differentiation Actin Filament-based Process Response To Calcium Ion Positive Regulation Of Catabolic Process Response To Radiation Response To Metal Ion Skeletal Muscle Thin Filament Assembly Phosphoserine Residue Binding Negative Regulation Of Potassium Ion Export Across Plasma Membrane Reproductive Behavior Regulation Of Caveolin-mediated Endocytosis Cytoskeleton Cellular Response To Metal Ion Sodium Channel Inhibitor Activity Positive Regulation Of Protein Metabolic Process Striated Muscle Thin Filament Outer Ear Morphogenesis Cellular Response To Salt Stress Potassium Channel Inhibitor Activity Regulation Of Cell Motility Identical Protein Binding
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